ID   A0A2Y9BJR0_9FIRM        Unreviewed;       468 AA.
AC   A0A2Y9BJR0;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=GPH family glycoside/pentoside/hexuronide:cation symporter/glucuronide carrier protein/probable glucitol transport protein GutA {ECO:0000313|EMBL:PWJ23436.1};
DE   SubName: Full=Glycoside/pentoside/hexuronide:cation symporter, GPH family/glucuronide carrier protein/probable glucitol transport protein GutA {ECO:0000313|EMBL:SSA57694.1};
GN   ORFNames=A8806_11462 {ECO:0000313|EMBL:PWJ23436.1}, SAMN05216536_11462
GN   {ECO:0000313|EMBL:SSA57694.1};
OS   Faecalicatena orotica.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Faecalicatena.
OX   NCBI_TaxID=1544 {ECO:0000313|EMBL:SSA57694.1, ECO:0000313|Proteomes:UP000251306};
RN   [1] {ECO:0000313|EMBL:SSA57694.1, ECO:0000313|Proteomes:UP000251306}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NLAE-zl-C242 {ECO:0000313|EMBL:SSA57694.1,
RC   ECO:0000313|Proteomes:UP000251306};
RA   Cai Z.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:PWJ23436.1, ECO:0000313|Proteomes:UP000245845}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NLAE-zl-C242 {ECO:0000313|EMBL:PWJ23436.1,
RC   ECO:0000313|Proteomes:UP000245845};
RA   Kelly W.;
RT   "The Hungate 1000. A catalogue of reference genomes from the rumen
RT   microbiome.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}.
CC   -!- SIMILARITY: Belongs to the sodium:galactoside symporter (TC 2.A.2)
CC       family. {ECO:0000256|ARBA:ARBA00009617}.
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DR   EMBL; QGDL01000014; PWJ23436.1; -; Genomic_DNA.
DR   EMBL; UETE01000014; SSA57694.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2Y9BJR0; -.
DR   Proteomes; UP000245845; Unassembled WGS sequence.
DR   Proteomes; UP000251306; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   CDD; cd17332; MFS_MelB_like; 1.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR   InterPro; IPR039672; MFS_2.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR001927; Na/Gal_symport.
DR   NCBIfam; TIGR00792; gph; 1.
DR   PANTHER; PTHR11328:SF24; INNER MEMBRANE SYMPORTER YICJ-RELATED; 1.
DR   PANTHER; PTHR11328; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13347; MFS_2; 1.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245845};
KW   Symport {ECO:0000256|ARBA:ARBA00022847};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022847}.
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        99..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        129..149
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        201..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        241..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        285..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        319..335
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        341..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        385..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        430..448
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   468 AA;  52126 MW;  CF811AF7452F9D5F CRC64;
     MSSRALRAEI PVNVKKRTDT NVRIPLISKV AYGMGDVGCN FSWMFVGNFL MIFYTDVFGI
     SMSAVAGLML FSRFWDAVND PVIGSLTDKT KSRWGRYRPW LLIAAPITAI VLMLTFWAHP
     DWPNTSKIVY MAVTYCILVL GYTCVNIPYG TLCGAMTQNI EERAQINTFR SVAAMIAIGI
     INIITVPLIS KLGAGNDKRG YLLIAVIYGC IFAACHIFCF SKTKEVVTIP EKQKVSIKEQ
     LKAVSVNKPY ILALAGQLLF GFTLYGRNAD ALYYFTYVEG NKAFFTTYSM CIIIPSIIGA
     ACFPLLFKWT NNKGRAASIF AFLTGISMLS LYLFSVRTSP ILFYGISGLT QFFFSGFNTA
     IYAIIPDCVE YGEWKTGLRN DGFQYAFVSL GNKIGMALGT SLLALVLGVA GYVANQQQNE
     TVIAVMKHSF TTIPGVFWVV TGIVLFFYRL NKKRYNEIVG EIKIRKEQ
//