ID   A0A2Y9BN02_9FIRM        Unreviewed;       449 AA.
AC   A0A2Y9BN02;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   24-JAN-2024, entry version 11.
DE   SubName: Full=GHKL domain-containing protein {ECO:0000313|EMBL:SSA58388.1};
GN   ORFNames=A8806_11967 {ECO:0000313|EMBL:PWJ21577.1}, SAMN05216536_11967
GN   {ECO:0000313|EMBL:SSA58388.1};
OS   Faecalicatena orotica.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Faecalicatena.
OX   NCBI_TaxID=1544 {ECO:0000313|EMBL:SSA58388.1, ECO:0000313|Proteomes:UP000251306};
RN   [1] {ECO:0000313|EMBL:SSA58388.1, ECO:0000313|Proteomes:UP000251306}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NLAE-zl-C242 {ECO:0000313|EMBL:SSA58388.1,
RC   ECO:0000313|Proteomes:UP000251306};
RA   Cai Z.;
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:PWJ21577.1, ECO:0000313|Proteomes:UP000245845}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NLAE-zl-C242 {ECO:0000313|EMBL:PWJ21577.1,
RC   ECO:0000313|Proteomes:UP000245845};
RA   Kelly W.;
RT   "The Hungate 1000. A catalogue of reference genomes from the rumen
RT   microbiome.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; QGDL01000019; PWJ21577.1; -; Genomic_DNA.
DR   EMBL; UETE01000019; SSA58388.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A2Y9BN02; -.
DR   OrthoDB; 9813149at2; -.
DR   Proteomes; UP000245845; Unassembled WGS sequence.
DR   Proteomes; UP000251306; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd16935; HATPase_AgrC-ComD-like; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR032834; NatK_C.
DR   Pfam; PF14501; HATPase_c_5; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000245845};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        35..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        65..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        94..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        126..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        155..173
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          327..432
FT                   /note="Sensor histidine kinase NatK C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14501"
SQ   SEQUENCE   449 AA;  52107 MW;  4640705D86809119 CRC64;
     MAGILLNTPK YYTVIAEILS CLLYIILFGQ KTRQIYQYVG LMVLSVVHIF YFIASDVIYN
     KIGTFFMAGT IILMYLFFMV GCRMDWRKRV YCTIRSLVLA EFMASMAWSL YLFLVRKFPI
     SRLTETIILL SVYLGIIFLL WNLERKASLG NEKIQIKYAS LFSCLIIGVG SYITSGLGIK
     YASAELAGEY GMALFSVRTL IDLAGVTMLY AHNMQLYNEQ VNQENYAIHT ILRNQEKQYQ
     FSQECIDMVN MKYHDLKQQI NIWKMSSGDL SYKKYMDELS RQMEQFDLSI HSGNQVIDTI
     LTEKTLLCAK KEIQIITVVD GKELDFMEVA DLCSIFGNAL DNAIEYEENL LDKEQRIIRV
     VVYRVHSFVL LMFENYCEIQ HKLYEGLPIS TKENKLLHGY GLKSIQYIVK KYDGQMDIVQ
     KDGWFKLKMI IPLPDENRGN SPELKIENK
//