ID A0A2Y9D7Q6_TRIMA Unreviewed; 444 AA.
AC A0A2Y9D7Q6;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=TFIIA-alpha and beta-like factor isoform X2 {ECO:0000313|RefSeq:XP_004369535.1};
GN Name=LOC101343997 {ECO:0000313|RefSeq:XP_004369535.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_004369535.1};
RN [1] {ECO:0000313|RefSeq:XP_004369535.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TFIIA subunit 1 family.
CC {ECO:0000256|ARBA:ARBA00010059}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_004369535.1; XM_004369478.1.
DR AlphaFoldDB; A0A2Y9D7Q6; -.
DR GeneID; 101343997; -.
DR OrthoDB; 9955at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0005672; C:transcription factor TFIIA complex; IEA:InterPro.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd07976; TFIIA_alpha_beta_like; 1.
DR Gene3D; 2.30.18.10; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
DR InterPro; IPR004855; TFIIA_asu/bsu.
DR InterPro; IPR009088; TFIIA_b-brl.
DR PANTHER; PTHR12694:SF9; TFIIA-ALPHA AND BETA-LIKE FACTOR; 1.
DR PANTHER; PTHR12694; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; 1.
DR Pfam; PF03153; TFIIA; 1.
DR SMART; SM01371; TFIIA; 1.
DR SUPFAM; SSF50784; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT REGION 273..338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 356..395
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..310
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..371
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..395
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 444 AA; 48264 MW; 864432A9EB517463 CRC64;
MACANSVLWE TKVLQSKATE DLFRNSVHSP LYTLQLPHGM HQTLQTSTAS LVVPAGRSIP
TFTTAELGTS NSSANFTFPS SIGYPIHVPA GVTLQTASGH LYKVNVPIIV TQTPGRASIL
QHPIQQVFQQ LGQPSVIQTG IPQLSPSSLH ATTEKPLRPE TVFQQPTILY SGAVDRKQVE
NVTTDIFVPP GNEHKVMSEA LLSQQESPQL ISVPGVVFAP QVSQLDSNVK LSVSASMTQT
LPGGPFSAGP RGALHQHLPD VQLRVLKNRM HGCDSVKQPR NIEEPSSLPV SEKDSNSQKD
LSTPSTDDDF NEIIQIDGAG DVSSSEEIGS SRDVDGNDFL GMVDAEQLKL LEEEGDSISN
DSTVNSNDNE DSQTEIVEED PLNSGDDDSE QDVPDLFDTD NVIVCQYDKI HRNKNKWKFY
LKDGVMCFGG KDFVFAKAIG DAEW
//
