ID A0A2Y9D7R1_TRIMA Unreviewed; 478 AA.
AC A0A2Y9D7R1;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=TFIIA-alpha and beta-like factor isoform X1 {ECO:0000313|RefSeq:XP_004369534.1};
GN Name=LOC101343997 {ECO:0000313|RefSeq:XP_004369534.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_004369534.1};
RN [1] {ECO:0000313|RefSeq:XP_004369534.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TFIIA subunit 1 family.
CC {ECO:0000256|ARBA:ARBA00010059}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_004369534.1; XM_004369477.2.
DR AlphaFoldDB; A0A2Y9D7R1; -.
DR STRING; 127582.A0A2Y9D7R1; -.
DR GeneID; 101343997; -.
DR KEGG; tmu:101343997; -.
DR InParanoid; A0A2Y9D7R1; -.
DR OrthoDB; 9955at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0005672; C:transcription factor TFIIA complex; IEA:InterPro.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd07976; TFIIA_alpha_beta_like; 2.
DR Gene3D; 1.10.287.100; -; 1.
DR Gene3D; 2.30.18.10; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
DR InterPro; IPR004855; TFIIA_asu/bsu.
DR InterPro; IPR009088; TFIIA_b-brl.
DR PANTHER; PTHR12694:SF9; TFIIA-ALPHA AND BETA-LIKE FACTOR; 1.
DR PANTHER; PTHR12694; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; 1.
DR Pfam; PF03153; TFIIA; 1.
DR SMART; SM01371; TFIIA; 1.
DR SUPFAM; SSF47396; Transcription factor IIA (TFIIA), alpha-helical domain; 1.
DR SUPFAM; SSF50784; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT REGION 307..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..344
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..405
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 406..429
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 478 AA; 52276 MW; A6BAF4051202C7EC CRC64;
MACANSVPTL YRSVIEDVIE RVRNLFAEEG IEEQVLKDLK QLWETKVLQS KATEDLFRNS
VHSPLYTLQL PHGMHQTLQT STASLVVPAG RSIPTFTTAE LGTSNSSANF TFPSSIGYPI
HVPAGVTLQT ASGHLYKVNV PIIVTQTPGR ASILQHPIQQ VFQQLGQPSV IQTGIPQLSP
SSLHATTEKP LRPETVFQQP TILYSGAVDR KQVENVTTDI FVPPGNEHKV MSEALLSQQE
SPQLISVPGV VFAPQVSQLD SNVKLSVSAS MTQTLPGGPF SAGPRGALHQ HLPDVQLRVL
KNRMHGCDSV KQPRNIEEPS SLPVSEKDSN SQKDLSTPST DDDFNEIIQI DGAGDVSSSE
EIGSSRDVDG NDFLGMVDAE QLKLLEEEGD SISNDSTVNS NDNEDSQTEI VEEDPLNSGD
DDSEQDVPDL FDTDNVIVCQ YDKIHRNKNK WKFYLKDGVM CFGGKDFVFA KAIGDAEW
//
