ID   A0A2Y9D8L7_TRIMA        Unreviewed;       843 AA.
AC   A0A2Y9D8L7;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=F-box only protein 11 {ECO:0000313|RefSeq:XP_004369539.1};
GN   Name=LOC101346184 {ECO:0000313|RefSeq:XP_004369539.1};
OS   Trichechus manatus latirostris (Florida manatee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX   NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_004369539.1};
RN   [1] {ECO:0000313|RefSeq:XP_004369539.1}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
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DR   RefSeq; XP_004369539.1; XM_004369482.2.
DR   AlphaFoldDB; A0A2Y9D8L7; -.
DR   SMR; A0A2Y9D8L7; -.
DR   STRING; 127582.A0A2Y9D8L7; -.
DR   GeneID; 101346184; -.
DR   KEGG; tmu:101346184; -.
DR   InParanoid; A0A2Y9D8L7; -.
DR   OrthoDB; 5491826at2759; -.
DR   Proteomes; UP000248480; Unplaced.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd22091; F-box_FBXO11; 1.
DR   CDD; cd19676; UBR-box_UBR6_FBXO11; 1.
DR   Gene3D; 1.20.1280.50; -; 1.
DR   Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 3.
DR   InterPro; IPR039448; Beta_helix.
DR   InterPro; IPR006633; Carb-bd_sugar_hydrolysis-dom.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR047505; F-box_FBXO11.
DR   InterPro; IPR047504; FBXO11_UBR-box.
DR   InterPro; IPR007742; NosD_dom.
DR   InterPro; IPR022441; Para_beta_helix_rpt-2.
DR   InterPro; IPR006626; PbH1.
DR   InterPro; IPR012334; Pectin_lyas_fold.
DR   InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR   InterPro; IPR003126; Znf_UBR.
DR   NCBIfam; TIGR03804; para_beta_helix; 4.
DR   PANTHER; PTHR22990; F-BOX ONLY PROTEIN; 1.
DR   PANTHER; PTHR22990:SF20; F-BOX ONLY PROTEIN 11; 1.
DR   Pfam; PF13229; Beta_helix; 2.
DR   Pfam; PF12937; F-box-like; 1.
DR   Pfam; PF05048; NosD; 1.
DR   Pfam; PF02207; zf-UBR; 1.
DR   SMART; SM00722; CASH; 3.
DR   SMART; SM00256; FBOX; 1.
DR   SMART; SM00710; PbH1; 19.
DR   SMART; SM00396; ZnF_UBR1; 1.
DR   SUPFAM; SSF81383; F-box domain; 1.
DR   SUPFAM; SSF51126; Pectin lyase-like; 3.
DR   PROSITE; PS50181; FBOX; 1.
DR   PROSITE; PS51157; ZF_UBR; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          69..115
FT                   /note="F-box"
FT                   /evidence="ECO:0000259|PROSITE:PS50181"
FT   DOMAIN          749..820
FT                   /note="UBR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51157"
FT   ZN_FING         749..820
FT                   /note="UBR-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00508"
FT   REGION          1..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        32..46
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   843 AA;  94015 MW;  B177B62DFEA5F524 CRC64;
     MVAEESGPGA QNSPYQLRRK TLLPKRTACP TKSSMEGAST STTENFGHRA KRARVSGKSQ
     DLSAAPAEQY LQEKLPDEVV LKIFSYLLEQ DLCRAACVCK RFSELANDPI LWKRLYMEVF
     EYTRPMMHPE PGKFYQINPE EYEHPNPWKE SFQQLYKGAH VKPGFAEHFY SNPARYKGRE
     NMLYYDTIED ALGGVQEAHF DGLIFVHSGI YTDEWIYIES PITMIGAAPG KVADKVIIEN
     TRDSTFVFME GSEDAYVGYM TIRFNPDDKS AQHHNAHHCL EITVNCSPII DHCIIRSTCT
     VGSAVCVSGQ GACPTIKHCN ISDCENVGLY ITDHAQGIYE DNEISNNALA GIWVKNHGNP
     IIRRNHIHHG RDVGVFTFDH GMGYFESCNI HRNRIAGFEV KAYANPTVVR CEIHHGQTGG
     IYVHEKGRGQ FIENKIYANN FAGVWITSNS DPTIRGNSIF NGNQGGVYIF GDGRGLIEGN
     DIYGNALAGI QIRTNSCPIV RHNKIHDGQH GGIYVHEKGQ GVIEENEVYS NTLAGVWVTT
     GSTPVLRRNR IHSGKQVGVY FYDNGHGVLE DNDIYNHMYS GVQIRTGSNP KIRRNKIWGG
     QNGGILVYNS GLGCIEDNEI FDNAMAGVWI KTDSNPTLRR NKIHDGRDGG ICIFNGGRGL
     LEENDIFRNA QAGVLISTNS HPVLRKNRIF DGFAAGIEIT NHATATLEGN QIFNNRFGGL
     FLASGVNVTM KDNKIMNNQD AIEKAVSRGQ CLYKISSYTS YPMHDFYRCH TCNTTDRNAI
     CVNCIKKCHQ GHDVEFIRHD RFFCDCGAGT LSNPCTLAGE PTHDTDTLYD SAPPIESNTL
     QHN
//