ID A0A2Y9DAI1_TRIMA Unreviewed; 414 AA.
AC A0A2Y9DAI1;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Acyl-coenzyme A thioesterase 1-like {ECO:0000313|RefSeq:XP_004371078.1};
GN Name=LOC101348829 {ECO:0000313|RefSeq:XP_004371078.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_004371078.1};
RN [1] {ECO:0000313|RefSeq:XP_004371078.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC {ECO:0000256|ARBA:ARBA00006538}.
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DR RefSeq; XP_004371078.1; XM_004371021.3.
DR AlphaFoldDB; A0A2Y9DAI1; -.
DR STRING; 127582.A0A2Y9DAI1; -.
DR GeneID; 101348829; -.
DR KEGG; tmu:101348829; -.
DR InParanoid; A0A2Y9DAI1; -.
DR OrthoDB; 5356064at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR GO; GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR InterPro; IPR014940; BAAT_C.
DR InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR PANTHER; PTHR10824:SF16; ACYL-COENZYME A THIOESTERASE 1-RELATED; 1.
DR PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR Pfam; PF08840; BAAT_C; 1.
DR Pfam; PF04775; Bile_Hydr_Trans; 1.
DR PIRSF; PIRSF016521; Acyl-CoA_hydro; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000248480}.
FT DOMAIN 16..140
FT /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT acid N-acetyltransferase"
FT /evidence="ECO:0000259|Pfam:PF04775"
FT DOMAIN 204..411
FT /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08840"
FT ACT_SITE 232
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT ACT_SITE 326
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT ACT_SITE 360
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
SQ SEQUENCE 414 AA; 45493 MW; 29F0558B147A134B CRC64;
MAATVILEPR GRCCWDQPVN IKVHRLAPEQ KVTLRASLRD EKGALFRAHA RYCADMDGEL
ELARAPALGG SFAGLEPMGL IWALEPEKPL LRLVKRDVQT PFAVALEVLE GHEPDPRRVL
GRTVHERDFL PTGVRREPVR AGRVRATLFL PPEPGPFPGV VDISGAGGGL PEYRASLLAG
KGFAVMALAY YNYEDLPKSL EILHLEYFEE AVNYLLNRPE VKGPGLGLLG ISKGGDLCLS
MASFLKGITA ATIINGSVAN IGGVLHYKDK TLPPLSANRN RIKVTKDGLV DIMDALNSPL
EGPDQKSFIP VERAECTFLF LVGLDDHNWK SEFYANEASN RLQAHCKEKP QIICYPGAGH
YIEPPYFPMC QASLHTLVGS PVIWGGEPRA HAMAQVDAWK QLQTFFHKHL GDGK
//
