ID A0A2Y9DBP0_TRIMA Unreviewed; 777 AA.
AC A0A2Y9DBP0;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Zinc finger FYVE domain-containing protein 1 isoform X2 {ECO:0000313|RefSeq:XP_004371066.1};
GN Name=LOC101346283 {ECO:0000313|RefSeq:XP_004371066.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_004371066.1};
RN [1] {ECO:0000313|RefSeq:XP_004371066.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_004371066.1; XM_004371009.2.
DR AlphaFoldDB; A0A2Y9DBP0; -.
DR GeneID; 101346283; -.
DR KEGG; tmu:101346283; -.
DR OrthoDB; 277036at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd19819; Bbox1_ZFYVE1_rpt1; 1.
DR CDD; cd19820; Bbox1_ZFYVE1_rpt2; 1.
DR CDD; cd15734; FYVE_ZFYV1; 1.
DR CDD; cd01851; GBP; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR042427; ZFYV1.
DR InterPro; IPR047856; ZFYVE1_first_BBox1.
DR InterPro; IPR047855; ZFYVE1_second_BBox1.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46624; AGAP002036-PA; 1.
DR PANTHER; PTHR46624:SF3; ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF01363; FYVE; 2.
DR SMART; SM00064; FYVE; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50178; ZF_FYVE; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 598..659
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT DOMAIN 715..775
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
SQ SEQUENCE 777 AA; 87152 MW; F967228B7A2C7F70 CRC64;
MSAQTNPAEK GRNPGLSCQE SYACSGTDEA VFECDECCSL QCLRCEEELH RQERLRNHER
IRLKPGHIPY CDPCKGPNGH SPGVRQRAAV RCQTCKINLC LECQKRTHSG GNKRRHPVTV
YHVTKVQESL EEEEMDEETK RKKMTEKVVS FLLVDENEEI QVTNEEDFIR KLDCKPDQHL
KVVSIFGNTG DGKSHTLNHT FFYGREVFKT SPAQESCTVG VWAAYDPVHK VAVIDTEGLL
GATVNLSQRT RLLLKVLAIS DLVIYRTHAD RLHNDLFKFL GDASEAYLKH FTKELKATTA
RCGLDVPLST LGPAVIIFHE TVHTQLLGSD HPSEVPEKLI QDRFRKLGRF PEAFSSIHYK
GTRTYNPPTD FSGLRRALEQ QLENNTTRSP RHPGVIFKAL KALSDRFSGE IPDDQMAHSS
FFPDEYFTCS SLCLSCGAGC KNSMNHGKEG VPHEAKSRCR YSHQYDNRVY TCKACYERGK
EVSVVPKTSA STDSPWMGLA KYAWSGYVIE CPNCGVVYRS RQYWFGNQDP VDTVVRTEIV
HVWPGTDAFL KDNNNAAQRL LDGMNFMAQS VSELSLGPTK AVTSWLTDQI APAYWRPNSQ
ILSCSKCATS FKDNDTKHHC RACGEGFCDS CSSKTRPVPE RGWGPAPVRV CDNCYDARNV
QLDVAEAQVD DEGGTLIARK VGEAVQNTLG AVVTAIDIPL GLVKDAARPA YWVPDHEILH
CHNCRKEFSI KLSKHHCRAC GQGFCDECSH DRRAVPSRGW DHPVRVCFNC NKKPGDL
//
