ID A0A2Y9DDA1_TRIMA Unreviewed; 409 AA.
AC A0A2Y9DDA1;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Failed axon connections homolog {ECO:0000313|RefSeq:XP_004372468.1};
GN Name=LOC101345954 {ECO:0000313|RefSeq:XP_004372468.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_004372468.1};
RN [1] {ECO:0000313|RefSeq:XP_004372468.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the FAX family. {ECO:0000256|ARBA:ARBA00006475}.
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DR RefSeq; XP_004372468.1; XM_004372411.2.
DR AlphaFoldDB; A0A2Y9DDA1; -.
DR STRING; 127582.A0A2Y9DDA1; -.
DR GeneID; 101345954; -.
DR KEGG; tmu:101345954; -.
DR InParanoid; A0A2Y9DDA1; -.
DR OrthoDB; 3684737at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR CDD; cd03193; GST_C_Metaxin; 1.
DR CDD; cd03080; GST_N_Metaxin_like; 1.
DR InterPro; IPR026928; FAX/IsoI-like.
DR InterPro; IPR045796; FAXC_N.
DR InterPro; IPR036282; Glutathione-S-Trfase_C_sf.
DR InterPro; IPR033468; Metaxin_GST.
DR InterPro; IPR012336; Thioredoxin-like_fold.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR12289:SF76; FAILED AXON CONNECTIONS HOMOLOG; 1.
DR PANTHER; PTHR12289; METAXIN RELATED; 1.
DR Pfam; PF19333; FAXC_N; 1.
DR Pfam; PF17171; GST_C_6; 1.
DR Pfam; PF17172; GST_N_4; 1.
DR SFLD; SFLDG01180; SUF1; 1.
DR SFLD; SFLDG01200; SUF1.1; 1.
DR SUPFAM; SSF47616; GST C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000248480}.
FT DOMAIN 1..106
FT /note="Failed axon connections homolog N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19333"
FT DOMAIN 117..211
FT /note="Thioredoxin-like fold"
FT /evidence="ECO:0000259|Pfam:PF17172"
FT DOMAIN 264..326
FT /note="Metaxin glutathione S-transferase"
FT /evidence="ECO:0000259|Pfam:PF17171"
FT REGION 371..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 409 AA; 46808 MW; 8F2A77B5365555E3 CRC64;
MHWGVGFASS RPCVVDLSWN QSVSFFGWWA GSEEPFSFYG DIIAFPLQDY GGIMAGLGSD
PWWKKTLYLT GGALLAAAAY LLHELLVIRK QQEIDSKDAI ILHQFARPNN GVPSLSPFCL
KMETYLRMAD LPYQNYFGGK LSAQGKMPWI EYNNEKVSGT EFIIDFLEEK LGVNLNKNLG
PHERAVSRAV TKMVEEHFYW TLAYCQWVDN LNETRKMLSL SGGGPFSNLL RWVVCHITKG
IVKREMHGHG IGRFSEEEIY RLMEKDMRSL AGLLGDKKYI MGPKLSTLDA TIFGHLAQAM
WTLPGTRPER LIKGELINLA MYCERIRRKF WPEWHHDDDN TIYESEESSE GSKTHTPLLD
FSFYSRTETF EDEGADNSFS RTPDTDFTGQ SLFDSDVDMD DYTDHEQCK
//
