ID   A0A2Y9DDU8_TRIMA        Unreviewed;       420 AA.
AC   A0A2Y9DDU8;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=LOW QUALITY PROTEIN: bile acid-CoA:amino acid N-acyltransferase {ECO:0000313|RefSeq:XP_004372274.2};
GN   Name=LOC101357199 {ECO:0000313|RefSeq:XP_004372274.2};
OS   Trichechus manatus latirostris (Florida manatee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX   NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_004372274.2};
RN   [1] {ECO:0000313|RefSeq:XP_004372274.2}
RP   IDENTIFICATION.
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC       {ECO:0000256|ARBA:ARBA00006538}.
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DR   RefSeq; XP_004372274.2; XM_004372217.2.
DR   STRING; 127582.A0A2Y9DDU8; -.
DR   KEGG; tmu:101357199; -.
DR   InParanoid; A0A2Y9DDU8; -.
DR   OrthoDB; 5356064at2759; -.
DR   Proteomes; UP000248480; Unplaced.
DR   GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR   InterPro; IPR014940; BAAT_C.
DR   InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR   InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR   PANTHER; PTHR10824:SF1; ACYL-COENZYME A AMINO ACID N-ACYLTRANSFERASE 1-RELATED; 1.
DR   PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR   Pfam; PF08840; BAAT_C; 1.
DR   Pfam; PF04775; Bile_Hydr_Trans; 1.
DR   PIRSF; PIRSF016521; Acyl-CoA_hydro; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000248480}.
FT   DOMAIN          14..141
FT                   /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT                   acid N-acetyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF04775"
FT   DOMAIN          205..415
FT                   /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08840"
FT   ACT_SITE        236
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT   ACT_SITE        330
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT   ACT_SITE        364
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
SQ   SEQUENCE   420 AA;  46605 MW;  CB3C45CFF6B4CD8E CRC64;
     MFQLTVTPAT AFADEPVHIR MTGLPPSQMV TFKVSLKDVK GNLFRSKAFY RANETGEVDQ
     EQDRAFGGDY VGVHPMGLFW SLKPERAFRR LLKQDMMNIP FWVTLDLYDS VCFQDLATAQ
     PRASQALQRS FSGPGMQRVQ IWEGRVRGAL FLPPGEGPFP GVTDLFGGIG GLVEFRASLL
     AAHGFAVLAL AYFAHEDLPK QLLEVDLEFF SMASNGFSFV LCLQIQKSGI GVISVCKGAE
     IGLAMACYLK QVEATICING FNTIFQVPLR YKDLVVKPIQ SVKEGIQIHI SGAVCIWYSM
     GDPRDVLNQQ STLPVEKAQG RILVIVGEND ECLNSRIYAE QTLDQLXSHG RSSGRILVYL
     RAGHLTEPPY APLCYASWSH GFSWPXLWGG DPAAHAAAQV HAWGEIQKFF RQYLVPTRSK
//