ID A0A2Y9DFU5_TRIMA Unreviewed; 572 AA.
AC A0A2Y9DFU5;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Protein disulfide-isomerase-like protein of the testis {ECO:0000313|RefSeq:XP_004373363.1};
GN Name=LOC101347654 {ECO:0000313|RefSeq:XP_004373363.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_004373363.1};
RN [1] {ECO:0000313|RefSeq:XP_004373363.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the protein disulfide isomerase family.
CC {ECO:0000256|ARBA:ARBA00006347}.
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DR RefSeq; XP_004373363.1; XM_004373306.1.
DR AlphaFoldDB; A0A2Y9DFU5; -.
DR STRING; 127582.A0A2Y9DFU5; -.
DR GeneID; 101347654; -.
DR KEGG; tmu:101347654; -.
DR InParanoid; A0A2Y9DFU5; -.
DR OrthoDB; 5399045at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR CDD; cd02961; PDI_a_family; 1.
DR CDD; cd02995; PDI_a_PDI_a'_C; 1.
DR CDD; cd02982; PDI_b'_family; 1.
DR CDD; cd02981; PDI_b_family; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 4.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR18929; PROTEIN DISULFIDE ISOMERASE; 1.
DR PANTHER; PTHR18929:SF58; PROTEIN DISULFIDE-ISOMERASE-LIKE PROTEIN OF THE TESTIS; 1.
DR Pfam; PF00085; Thioredoxin; 1.
DR Pfam; PF13848; Thioredoxin_6; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 4.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..572
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5016120635"
FT DOMAIN 365..490
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT REGION 541..572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..572
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 572 AA; 66254 MW; D6487A031CD27A6B CRC64;
MELLWTPLLL VASCVAAVLG SPEVDLKEVS QPLHIREEGN LLVLTSAGLT QMLNQTRFLM
VIFHNPSSKR SRNLAEELGR AVEIMGKGKN GLGFGKVDIT TEKELQEEFN IKKAPEVKLF
FEGNRSEPIS CEGVVESAAL VVWLRRQISK KAFLFNNSQQ VVEFVRSRPL VIVGFFQDLE
EEVAELFYDV IKDFPELTFG VISIPNTIGR FHVTLDSVLV FKKGKVVNRQ ELINDSTNKQ
VLSQVIKQHL TDLVIEYNTE NKDLIYELNI LNHMMLFVSK SSESFGTIIQ QYRLTSKEFQ
NKILFILVNT DEPRNRRVFE YFRITEVDIP SVQILNLTSD VRYKMPAEEI TYENLKKFGI
SFLSRSAKKH QSSEELPKYW DQGPVKQLVG KNFHIVVFDK ERDVFVMFYA PWSKKCRALF
PLWEELGRKY QNHSTVTIAK IDITANDIQL MNLDRYPFFR FFPINSEQGV IYKGEYTVKG
FSDFLESQIN TRIEEEDEIL FVEQSELVEE KVLPEEEEET FEKKELSEQK LPVLENVTRL
EEPDGQKELV EEVAKPMGPP RQEKKPRVKE EL
//
