ID A0A2Y9DVD4_TRIMA Unreviewed; 505 AA.
AC A0A2Y9DVD4;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Tubby-like protein {ECO:0000256|RuleBase:RU361125};
GN Name=LOC101357142 {ECO:0000313|RefSeq:XP_004381735.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_004381735.1};
RN [1] {ECO:0000313|RefSeq:XP_004381735.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the TUB family. {ECO:0000256|ARBA:ARBA00007129,
CC ECO:0000256|RuleBase:RU361125}.
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DR RefSeq; XP_004381735.1; XM_004381678.1.
DR AlphaFoldDB; A0A2Y9DVD4; -.
DR STRING; 127582.A0A2Y9DVD4; -.
DR GeneID; 101357142; -.
DR KEGG; tmu:101357142; -.
DR InParanoid; A0A2Y9DVD4; -.
DR OrthoDB; 603296at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR025659; Tubby-like_C.
DR InterPro; IPR000007; Tubby_C.
DR InterPro; IPR018066; Tubby_C_CS.
DR InterPro; IPR005398; Tubby_N.
DR PANTHER; PTHR16517; TUBBY-RELATED; 1.
DR PANTHER; PTHR16517:SF24; TUBBY-RELATED PROTEIN 2; 1.
DR Pfam; PF01167; Tub; 1.
DR Pfam; PF16322; Tub_N; 1.
DR PRINTS; PR01573; SUPERTUBBY.
DR PRINTS; PR01574; TUBBYPROTEIN.
DR SUPFAM; SSF54518; Tubby C-terminal domain-like; 1.
DR PROSITE; PS01200; TUB_1; 1.
DR PROSITE; PS01201; TUB_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 27..235
FT /note="Tubby N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16322"
FT DOMAIN 256..499
FT /note="Tubby C-terminal"
FT /evidence="ECO:0000259|Pfam:PF01167"
FT REGION 32..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 207..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..68
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 505 AA; 56951 MW; 8A271FD24DD42B85 CRC64;
MSQENDTWKK EALVDELAAM RLQKLEQQRR LFEKKQRRKR QEPLMVHANP DASLRSRRPW
RREERLGSDS GPGNPFLLEN VPEAHLRNAF STVSCGGDGS GERRPLEFPT EADSSDPDLE
EVSVENVPAS PPPYKEPPGT LRRRGWPACQ RPGASAEDES EFQDGRDQYR GHSLGPPGME
SDWQLRDLTC KGEDLEVKKE ELEFAMRDSP AAAKEEVPQY PEGEDGTGSG DVGNTHRSPL
RAPGPRLGED MKAYVLRPAL RGHAVQCRIS RDKRGVDKGM FPFYYLYLEA ADGRKHFLLA
GRKRKRSKTS NYLISLDPTD LSRDGDNFVG KVRSNILGTK FTIFDNGVNP DRKNFVPETA
RIREELGAVC YETNVLGFRG PRKMTVIIPG FDAQNRRFRV QPQNEQESLL SRLQRGASQG
LILLQNKAPS WSDESGAYVL NFHGRVTRAS VKNFQIVHPD DPDYLVLQFG RVAPDSFTMD
FRFPLCPLQA FAICLSSFDG KLACE
//
