ID A0A2Y9DVH0_TRIMA Unreviewed; 531 AA.
AC A0A2Y9DVH0;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Zinc finger protein 350-like {ECO:0000313|RefSeq:XP_004381790.2};
GN Name=LOC101349213 {ECO:0000313|RefSeq:XP_004381790.2};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_004381790.2};
RN [1] {ECO:0000313|RefSeq:XP_004381790.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_004381790.2; XM_004381733.3.
DR AlphaFoldDB; A0A2Y9DVH0; -.
DR KEGG; tmu:101349213; -.
DR InParanoid; A0A2Y9DVH0; -.
DR OrthoDB; 5264074at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 8.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR PANTHER; PTHR23232:SF137; ZINC FINGER PROTEIN 8; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 8.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 8.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 8.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 8.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 8..79
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 204..231
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 232..259
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 260..287
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 288..315
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 316..343
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 344..371
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 372..399
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 400..427
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 427..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 437..451
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 531 AA; 60737 MW; FCEE61BEC6289114 CRC64;
MIKAQESVTF NDVAVEFTWE EWQLLLPAQK DLYQDVMLEN YSNLVSVGYQ VSEPNAPCKL
KRGEQPWPIQ DEIHSQNFSE IWKADDHLPG HSQNEWVNRM EKCHEHNAYE YIFNQHKSHF
TLHQNDGMFD LLGKTIKSNL SLISHSRSYG VKNSAELNGD EKTFPHANHE QFHMEIKFSE
SQKSNSMKSQ LIKHKRTHKI EKSHVCSECG KAFIKKSWLT DHQIIHTGEK PHRCNLCGKA
FSRKFMLTEH QRTHTGEKPY ECTECGKAFL KKSRLNIHQK THTGEKPYTC SECGKGFIQK
GNLIVHQRIH TGEKPYICSD CGKGFIQKTC LIAHQRFHTG KTPFVCSECG KSCSQKSGLI
KHQRIHTGEK PFQCSDCGKA FATKQKLIVH QRTHTGERPY GCTECGKTFA YMSCLVKHKR
IHTREKHVDS VKVEAPSAVR HSSSHTSDLM QDENPVNKAT IQMPSVAAQT SVDISGILPN
RNIVIVRQPV ARCEPSGDNR EFVQERNIMN AVNVVVPSVI NYILYYVTEN P
//
