ID A0A2Y9E2R8_TRIMA Unreviewed; 949 AA.
AC A0A2Y9E2R8;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Zinc finger protein 268 isoform X1 {ECO:0000313|RefSeq:XP_004385118.1, ECO:0000313|RefSeq:XP_023595058.1};
GN Name=LOC101359917 {ECO:0000313|RefSeq:XP_004385118.1,
GN ECO:0000313|RefSeq:XP_023595058.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_004385118.1};
RN [1] {ECO:0000313|RefSeq:XP_004385118.1, ECO:0000313|RefSeq:XP_023595058.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_004385118.1; XM_004385061.2.
DR RefSeq; XP_023595058.1; XM_023739290.1.
DR GeneID; 101359917; -.
DR KEGG; tmu:101359917; -.
DR OrthoDB; 4637982at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 24.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24381; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR24381:SF125; ZINC FINGER PROTEIN 949; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 23.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 23.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 14.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 21.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 24.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 82..153
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 278..305
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 306..333
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 334..361
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 362..389
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 390..417
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 418..445
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 446..473
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 474..501
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 502..529
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 530..557
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 558..585
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 586..613
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 614..641
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 642..669
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 670..697
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 698..725
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 726..753
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 754..781
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 782..809
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 810..837
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 838..865
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 866..893
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 894..921
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 922..949
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 31..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 949 AA; 109166 MW; 92E25B1655491456 CRC64;
MATRIRTASV WVPPLLERDN PCDIRIRKLP GQEPILGEET PDQRPLPGAP GWSQTSHRTG
RVLEWLLIYQ KQPETTKSWG PLSFKDVFVD FTWEEWRLLD PAQKSLYRTV MLENYSNLMS
LGYQHTKPDI IFKFKQGEEL RMIKAQIPNQ SFPEKVREID HNMEWQHENQ GKLGSVAKGY
EYTTFKKLCL STDYVSSRQK LHKCDTHGKS LKYNIGLNSN YAGTNPNGIH VHKESFLDPK
HEETLIGIKY CESNKAGKAI HKKSQLVCQQ MCMREKPFEC SYCGISFSSR SYLEVHQQTH
AEEQRYKCNE CRKEFSSKSY FIVHQRTHAG EKLHECSQCG KTFSFNSQLV IHQRIHTNDN
SYECCEGGKV FSRKDHLISF QRTHSGQKSY GCNECGKSFG LKSQLIIHQR IRTGEKPYEC
SECQKAFNTK SNLMVHQRTQ TREKPYACSE CGKTFTFQSQ LIVHQGVHTG VKPYACIQCG
KAFSLKSQLI VHQRSHTEVK PYVCSECVKA FRSKSYLFIH TRTHTGEKLH ECKECGKAFS
FNSQLVIHQR IHKGENPYEC HECGKAFSRK YQLISHQRTH AGEKPYECSD CGKAFGLKSQ
LIIHLRTHTG EKPFECSECR KAFNTKSNLI VHQRTHTGEK PYGCSECGKA FTFKSQLIVH
QGVHTGVKPY ACIQCGKAFS LKSQLIVHQR SHTEVKPYGC SECGKAFRSK SYLIIHMRTH
TGEKPHECNE CGKSFSFNSQ LIVHQRIHTG ENPYECSECG KGFNRKDQLI SHQRTHAGEK
PYGCSDCRKA FSSKSYLIIH MRTHSGEKPY ECSECGKAFI WKSLLIVHER THAVKNPYKC
SQCEKSFSGK LRLVIHQRMH MREKPYGCGE CDKAFIRKSQ LIVHQRTHSG EKPYGCNDCG
KTFSQKSILS AHQRTHTGEK PCKCTECGKA FCWKSQLIMH QRTHTDEKT
//
