ID A0A2Y9E2S2_TRIMA Unreviewed; 783 AA.
AC A0A2Y9E2S2;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Clathrin coat assembly protein AP180 isoform X3 {ECO:0000313|RefSeq:XP_004386102.1};
GN Name=LOC101355475 {ECO:0000313|RefSeq:XP_004386102.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_004386102.1};
RN [1] {ECO:0000313|RefSeq:XP_004386102.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_004386102.1; XM_004386045.1.
DR AlphaFoldDB; A0A2Y9E2S2; -.
DR GeneID; 101355475; -.
DR OrthoDB; 3667239at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0030136; C:clathrin-coated vesicle; IEA:InterPro.
DR GO; GO:0005545; F:1-phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0048268; P:clathrin coat assembly; IEA:InterPro.
DR GO; GO:0072583; P:clathrin-dependent endocytosis; IEA:InterPro.
DR Gene3D; 1.20.58.150; ANTH domain; 1.
DR InterPro; IPR011417; ANTH_dom.
DR InterPro; IPR014712; ANTH_dom_sf.
DR InterPro; IPR045192; AP180-like.
DR InterPro; IPR013809; ENTH.
DR PANTHER; PTHR22951; CLATHRIN ASSEMBLY PROTEIN; 1.
DR PANTHER; PTHR22951:SF4; CLATHRIN COAT ASSEMBLY PROTEIN AP180; 1.
DR Pfam; PF07651; ANTH; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000248480}.
FT DOMAIN 1..26
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 167..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 274..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 386..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 744..783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..204
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..307
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 783 AA; 78965 MW; BE0B6D1086290357 CRC64;
MSTFIRRYSR YLNEKAFSYR QMAFDFARVK KGADGVMRTM APEKLLKSMP ILQGQIDALL
EFDVHPNELT NGVINAAFML LFKDLIKLFA CYNDGVINLL EKFFEMKKGQ CKDALEIYKR
FLTRMTRVSE FLKVAEQVGI DKGDIPDLTQ APSSLMETLE QHLNTLEGKK SGNNEGSGAP
SPLSKSSPAT TVTSPNSTPA KTIDTSPPVD LFATASAAAP VSTSKPSSDL LDLQPDFSPG
GAAAAAAPAP PPPSGGATTW GDLLGEDSLA ALSSVPSEAQ ISDPFAPEPT PPTTTAEIAT
ASASASTTTT ITAVTAEVDL FGDAFAASPG EAPAASEGAT APAPPTPVAA ALDACSGNDP
FAPSEGSAEA APELDLFAMK PPETSVPVVT PTASTAPPVP ATAPSPAPAV AAASAATTAA
TAATTTATTS ATTTTTAPPA LDIFGDLFES APEVTAAPKP DAAAPSIDLF GTDAFSSPPH
GISPVPESSL TADLLSVDAF AAPSPATTAS PAKVDSSGVI DLFGDAFGSS ASEPQPAPQA
ASSSSASADL LAGFGGTFMA PSPSPVTPAQ NNLLQPNFEA AFGTTPSTSS SSSFDPSGDL
LMPTMAPTGQ PTPVSVVPPS PAMAASKALG SDLDSSLASL VGNLGISGTT SKKGDLQWNA
GEKKLTGGAN WQPKVAPATW SAGVPPSAPL QGAVPPTSSV PPVAGAPSVG QPGAGFGMPP
AGTGMPMMPQ QPVMFAQPMM RPPFGAAAVP GTQLSPSPTP ATQSPKKPPA KDPLADLNIK
DFL
//
