ID A0A2Y9E5J3_TRIMA Unreviewed; 354 AA.
AC A0A2Y9E5J3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Retinoic acid-induced protein 3 {ECO:0000313|RefSeq:XP_004387384.1};
GN Name=LOC101360795 {ECO:0000313|RefSeq:XP_004387384.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_004387384.1};
RN [1] {ECO:0000313|RefSeq:XP_004387384.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_004387384.1; XM_004387327.1.
DR AlphaFoldDB; A0A2Y9E5J3; -.
DR STRING; 127582.A0A2Y9E5J3; -.
DR GeneID; 101360795; -.
DR KEGG; tmu:101360795; -.
DR InParanoid; A0A2Y9E5J3; -.
DR OrthoDB; 4263681at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR CDD; cd15279; 7tmC_RAIG1_4_GPRC5A_D; 1.
DR InterPro; IPR017978; GPCR_3_C.
DR PANTHER; PTHR14511; G PROTEIN COUPLED RECEPTOR, CLASS C, GROUP 5; 1.
DR PANTHER; PTHR14511:SF7; RETINOIC ACID-INDUCED PROTEIN 3; 1.
DR Pfam; PF00003; 7tm_3; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 26..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 213..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 245..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 21..264
FT /note="G-protein coupled receptors family 3 profile"
FT /evidence="ECO:0000259|Pfam:PF00003"
FT REGION 335..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 354 AA; 39706 MW; 91204AD65D22FDF3 CRC64;
MATTIPPGCH KDLGSKYYRL CDMKEAWGIV LETLAAFGAV TSIAFMLAIL ILISKVQDTS
KRKMLPTQFL FLLGVLGVFG LTFAFIIKLD KETGPTRFFL FGILFALCFS CLLAHAFNLT
KLVRGRQPLS SLMILGLALG FSLVQDIIAV EYTVLTVSRT NTSIFSELSF SRRNEDFVML
LIYILILMVL TFLTSASTFC GSFTGWKRHG AHIFLTTLLS IAIWVAWITL LLISNPGPRW
DDTILSSALV ANGWVFLLIY VVPEFLLLTN QQNPRNYPGE EDFCKPQLMK QTTGVENRAY
SQEEITQGFE ETGDTLSAPY STHFPLQNQI PRKDFSIPRA HSPYSDYEGR EEGS
//
