ID A0A2Y9E709_TRIMA Unreviewed; 135 AA.
AC A0A2Y9E709;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Protein tyrosine phosphatase type IVA 3 {ECO:0000313|RefSeq:XP_004387424.1};
GN Name=LOC101352826 {ECO:0000313|RefSeq:XP_004387424.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_004387424.1};
RN [1] {ECO:0000313|RefSeq:XP_004387424.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000256|ARBA:ARBA00004412}.
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DR RefSeq; XP_004387424.1; XM_004387367.2.
DR AlphaFoldDB; A0A2Y9E709; -.
DR STRING; 127582.A0A2Y9E709; -.
DR GeneID; 101352826; -.
DR KEGG; tmu:101352826; -.
DR InParanoid; A0A2Y9E709; -.
DR OrthoDB; 117411at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR InterPro; IPR020422; TYR_PHOSPHATASE_DUAL_dom.
DR PANTHER; PTHR23339:SF119; PROTEIN TYROSINE PHOSPHATASE TYPE IVA 3; 1.
DR PANTHER; PTHR23339; TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE; 1.
DR Pfam; PF00102; Y_phosphatase; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50054; TYR_PHOSPHATASE_DUAL; 1.
PE 4: Predicted;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Methylation {ECO:0000256|ARBA:ARBA00022481};
KW Prenylation {ECO:0000256|ARBA:ARBA00023289};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480}.
FT DOMAIN 8..135
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50054"
FT DOMAIN 82..135
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
SQ SEQUENCE 135 AA; 14882 MW; 62858F2CD07700E7 CRC64;
MARMNRPAPV EVSYKNMRFL ITHNPTNATL NTFIEDLKKY GATTVVRVCE VTYDKAPLEK
DGITVVDWPF DDGAPPPGKV VEDWLSLLKA KFCDDPGSCV AVHCVAGLGR APVLVALALI
ESGMKYEDAI QFIRQ
//
