ID A0A2Y9EA06_TRIMA Unreviewed; 247 AA.
AC A0A2Y9EA06;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Membrane-associated progesterone receptor component 2 {ECO:0000313|RefSeq:XP_004389331.1};
GN Name=LOC101349166 {ECO:0000313|RefSeq:XP_004389331.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_004389331.1};
RN [1] {ECO:0000313|RefSeq:XP_004389331.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the cytochrome b5 family. MAPR subfamily.
CC {ECO:0000256|ARBA:ARBA00038357}.
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DR RefSeq; XP_004389331.1; XM_004389274.1.
DR AlphaFoldDB; A0A2Y9EA06; -.
DR STRING; 127582.A0A2Y9EA06; -.
DR GeneID; 101349166; -.
DR KEGG; tmu:101349166; -.
DR InParanoid; A0A2Y9EA06; -.
DR OrthoDB; 148785at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR PANTHER; PTHR10281:SF24; MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT 2; 1.
DR PANTHER; PTHR10281; MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED; 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR SMART; SM01117; Cyt-b5; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_004389331.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 78..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 127..225
FT /note="Cytochrome b5 heme-binding"
FT /evidence="ECO:0000259|SMART:SM01117"
FT REGION 1..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 226..247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 247 AA; 26267 MW; C9BE95838F336BDA CRC64;
MGGAGRGVGE GRGRGRGGRR WRAVMAADDG NVKLGTLGSG SDSSSDGSSE SPGGAVAAAE
GGGWAAAALA LLTGGGEMLL NVVLVALVLL GAYRLWVRWG RRGLGSGAGA GEESPAASLP
RMKKRDFSLE QLRQYDGSHN PRILLAVNGK VFDVTKGSKF YGPAGPYGIF AGRDASRGLA
TFCLDKDALR DEYDDLSDLN AVQMESVREW EMQFKEKYDY VGRLLKPGEE PSEYTDEEDT
KDHSKQD
//
