ID A0A2Y9EHK7_PHYMC Unreviewed; 392 AA.
AC A0A2Y9EHK7;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Speckle-type POZ protein-like isoform X2 {ECO:0000313|RefSeq:XP_007102523.1};
GN Name=SPOPL {ECO:0000313|RefSeq:XP_007102523.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007102523.1};
RN [1] {ECO:0000313|RefSeq:XP_007102523.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007102523.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the Tdpoz family.
CC {ECO:0000256|ARBA:ARBA00010846}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_007102523.1; XM_007102461.4.
DR AlphaFoldDB; A0A2Y9EHK7; -.
DR Ensembl; ENSPCTT00005001050; ENSPCTP00005000941; ENSPCTG00005000729.
DR GeneID; 102976090; -.
DR CTD; 339745; -.
DR OrthoDB; 5473088at2759; -.
DR Proteomes; UP000248484; Chromosome 2.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0030163; P:protein catabolic process; IEA:UniProt.
DR CDD; cd18519; BACK_SPOPL; 1.
DR CDD; cd18343; BTB_POZ_SPOPL; 1.
DR Gene3D; 6.10.250.3030; -; 1.
DR Gene3D; 6.20.250.50; -; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR002083; MATH/TRAF_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR008974; TRAF-like.
DR PANTHER; PTHR24413; SPECKLE-TYPE POZ PROTEIN; 1.
DR PANTHER; PTHR24413:SF91; SPECKLE-TYPE POZ PROTEIN-LIKE; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF00917; MATH; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00061; MATH; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS50144; MATH; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000248484}.
FT DOMAIN 31..161
FT /note="MATH"
FT /evidence="ECO:0000259|PROSITE:PS50144"
FT DOMAIN 200..262
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 392 AA; 44521 MW; BC7A4215719EDE4F CRC64;
MSREPTPPLS GDMSAGPIAE SWCYTQVKVV KFSYMWTINN FSFCREEMGE VLKSSTFSSS
PSDKMKWCLR VNPKGLDDES KDYLSLYLLL VSCPKSEVRA KFKFSLLNAK REETKAMESQ
RAYRFVQGKD WGFKKFIRRD FLLDEANGLL PDDKLTLFCE VSVVQDSVNI SGHTNTNTLK
VPECRLADDL GNLWENTRFT DCSFFVRGQE FKAHKSVLAA RSPVFNAMFE HEMEESKKNR
VEINDVDPEV FKEMMRFIYT GKAPNLDKMA DNLLAAADKY ALERLKVMCE EALCSNLSVE
NVADTLVLAD LHSAEQLKAQ AIDFINRCSV LRQLGCKDGK NWNGNQAADI METSGWKSMI
QSHPHLVAEA FRALASAQCP QFGIPRKRLK QS
//
