ID A0A2Y9EM00_PHYMC Unreviewed; 525 AA.
AC A0A2Y9EM00;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Tigger transposable element-derived protein 2 {ECO:0000313|RefSeq:XP_007105152.1, ECO:0000313|RefSeq:XP_028347397.1};
GN Name=TIGD2 {ECO:0000313|RefSeq:XP_007105152.1,
GN ECO:0000313|RefSeq:XP_028347397.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007105152.1};
RN [1] {ECO:0000313|RefSeq:XP_007105152.1, ECO:0000313|RefSeq:XP_028347397.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007105152.1,
RC ECO:0000313|RefSeq:XP_028347397.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00320}.
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DR RefSeq; XP_007105152.1; XM_007105090.3.
DR RefSeq; XP_028347397.1; XM_028491596.2.
DR STRING; 9755.ENSPCTP00005004110; -.
DR Ensembl; ENSPCTT00005004535; ENSPCTP00005004110; ENSPCTG00005002958.
DR GeneID; 102978339; -.
DR KEGG; pcad:102978339; -.
DR CTD; 166815; -.
DR OrthoDB; 2967227at2759; -.
DR Proteomes; UP000248484; Chromosome 7.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR InterPro; IPR004875; DDE_SF_endonuclease_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR006600; HTH_CenpB_DNA-bd_dom.
DR InterPro; IPR007889; HTH_Psq.
DR PANTHER; PTHR19303:SF22; TIGGER TRANSPOSABLE ELEMENT-DERIVED PROTEIN 2; 1.
DR PANTHER; PTHR19303; TRANSPOSON; 1.
DR Pfam; PF04218; CENP-B_N; 1.
DR Pfam; PF03184; DDE_1; 1.
DR Pfam; PF03221; HTH_Tnp_Tc5; 1.
DR SMART; SM00674; CENPB; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR PROSITE; PS51253; HTH_CENPB; 1.
DR PROSITE; PS50960; HTH_PSQ; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Nucleus {ECO:0000256|PROSITE-ProRule:PRU00320};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484}.
FT DOMAIN 1..52
FT /note="HTH psq-type"
FT /evidence="ECO:0000259|PROSITE:PS50960"
FT DOMAIN 67..139
FT /note="HTH CENPB-type"
FT /evidence="ECO:0000259|PROSITE:PS51253"
FT DNA_BIND 28..48
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00320"
FT REGION 447..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..474
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 525 AA; 59528 MW; CA16485AB71A09D4 CRC64;
MLGKRKRVVL TIKDKLDIIK KLEEGISFKK LSLVYGIGES TVRDIKKNKE RIINYANSSD
PTSGASKRKS MKSSTYEELD RVMIEWFNQQ KTNGIPVSGA ICAKQAKFFF DALGMEGDFN
ASSGWLTRFK QRHGIPKAAG KGTKLKGDET AASEFCGNFQ EFVERENLQP EQIYGADQTG
LFWKCLPSRT FALETERSAS GYRSSRERII IMCCANATGL HKLNLCVVGK AKKPRAFKGA
DLSNLPVTYF SQKSAWIEHS VFRQWFEKYF VPQVQKHLKS KGLLEKAVLL LDFPPAHPNE
ELLSSDDGRI IVKYLPPNVT SLIQPMSQGV LATVKRYYRA GLLQKYMDEG IDPKMFWKNL
TVLDAIYEVS RAWNMVKSST ITKAWKKLFP GNEENSGMNI DEGAILAANL ATVLQNTEDC
EHVDLENIDQ WFDSGSNDAC CRVLSDSEGA EDQAKPAEHR PSSKTRKAEL NPEKHISHKA
ALEWTENLLD YLEQQDDMLL SDKLVLRRLR TIIRRKQKIQ INKSH
//
