ID A0A2Y9EPD8_PHYMC Unreviewed; 374 AA.
AC A0A2Y9EPD8;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Protein NDRG1 {ECO:0000256|ARBA:ARBA00015429};
DE AltName: Full=N-myc downstream-regulated gene 1 protein {ECO:0000256|ARBA:ARBA00031987};
GN Name=NDRG1 {ECO:0000313|RefSeq:XP_007106496.1,
GN ECO:0000313|RefSeq:XP_007106498.1, ECO:0000313|RefSeq:XP_054938254.1,
GN ECO:0000313|RefSeq:XP_054938255.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007106496.1};
RN [1] {ECO:0000313|RefSeq:XP_007106496.1, ECO:0000313|RefSeq:XP_007106498.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007106496.1,
RC ECO:0000313|RefSeq:XP_007106498.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the NDRG family.
CC {ECO:0000256|ARBA:ARBA00005598}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_007106495.1; XM_007106433.1.
DR RefSeq; XP_007106496.1; XM_007106434.3.
DR RefSeq; XP_007106497.1; XM_007106435.1.
DR RefSeq; XP_007106498.1; XM_007106436.4.
DR RefSeq; XP_054938254.1; XM_055082279.1.
DR RefSeq; XP_054938255.1; XM_055082280.1.
DR STRING; 9755.ENSPCTP00005017977; -.
DR Ensembl; ENSPCTT00005019817; ENSPCTP00005017977; ENSPCTG00005012765.
DR GeneID; 102986442; -.
DR KEGG; pcad:102986442; -.
DR CTD; 10397; -.
DR OrthoDB; 5352016at2759; -.
DR Proteomes; UP000248484; Unplaced.
DR GO; GO:0005912; C:adherens junction; IEA:Ensembl.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005874; C:microtubule; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0055038; C:recycling endosome membrane; IEA:Ensembl.
DR GO; GO:0045296; F:cadherin binding; IEA:Ensembl.
DR GO; GO:0043015; F:gamma-tubulin binding; IEA:Ensembl.
DR GO; GO:0008017; F:microtubule binding; IEA:Ensembl.
DR GO; GO:0031267; F:small GTPase binding; IEA:Ensembl.
DR GO; GO:0071456; P:cellular response to hypoxia; IEA:Ensembl.
DR GO; GO:0030330; P:DNA damage response, signal transduction by p53 class mediator; IEA:Ensembl.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR004142; NDRG.
DR PANTHER; PTHR11034; N-MYC DOWNSTREAM REGULATED; 1.
DR PANTHER; PTHR11034:SF18; PROTEIN NDRG1; 1.
DR Pfam; PF03096; Ndr; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 325..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..343
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..374
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 374 AA; 40645 MW; 9806711283BDF339 CRC64;
MSRELQDVDL AEVKPLVEKG ETITGLLQEF DVQEQDIETL HGSIHVTLCG TPKGNRPVIL
TYHDIGMNHK TCYNPLFNSE DMQEITQHFA VCHVDAPGQQ DSAASFPTGY MYPSMDQLAE
MLPGVLHQFG LKSIIGMGTG AGAYILTRFA LNNPEMVEGL VLINVNPCAE GWMDWAASKI
SGWTQALPDM VMSHLFGKEE MQNNVEVVHT CRQHIMNDMN PGNLHLFINV YNSRRDLEIE
RPMPGTHTVT LQCPALLVVG DSSPAVDAVV ECNSKLDPTK TTLLKMADCG GLPQISQPAK
LAEAFKYFVQ GMGYMPSASM TRLMRSRTAS GSSVTSLEGV RSRSHTSEGA RLDIVPNSGG
SGSSAGPNST EVSC
//
