ID A0A2Y9ER88_PHYMC Unreviewed; 452 AA.
AC A0A2Y9ER88;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Polypyrimidine tract-binding protein 3 isoform X5 {ECO:0000313|RefSeq:XP_007106787.2};
GN Name=PTBP3 {ECO:0000313|RefSeq:XP_007106787.2};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007106787.2};
RN [1] {ECO:0000313|RefSeq:XP_007106787.2}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007106787.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007106787.2; XM_007106725.4.
DR AlphaFoldDB; A0A2Y9ER88; -.
DR Proteomes; UP000248484; Chromosome 9.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006397; P:mRNA processing; IEA:InterPro.
DR GO; GO:0045595; P:regulation of cell differentiation; IEA:InterPro.
DR CDD; cd12784; RRM2_ROD1; 1.
DR CDD; cd12703; RRM4_ROD1; 1.
DR Gene3D; 3.30.70.330; -; 4.
DR InterPro; IPR006536; HnRNP-L/PTB.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR021790; PTBP1-like_RRM2.
DR InterPro; IPR033110; PTBP3_RRM4.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01649; hnRNP-L_PTB; 1.
DR PANTHER; PTHR15592; MATRIN 3/NUCLEAR PROTEIN 220-RELATED; 1.
DR PANTHER; PTHR15592:SF17; POLYPYRIMIDINE TRACT-BINDING PROTEIN 3; 1.
DR Pfam; PF13893; RRM_5; 2.
DR Pfam; PF11835; RRM_8; 1.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 3.
DR PROSITE; PS50102; RRM; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 82..158
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 258..332
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 375..450
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 335..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 452 AA; 48884 MW; EF449B3A46FF0EF7 CRC64;
MASEEAAVTM VNYYTPVTPH LRSQPVFIQY SNHRELKTDN LPNQARAQAA LQAVSAVQSG
SLALPGAPAN EGTVLPGQSP VLRIIIENLF YPVTLEVLHQ IFSKFGTVLK IITFTKNNQF
QALLQYADPL NAHYAKMALD GQNIYNACCT LRIDFSKLTS LNVKYNNDKS RDFTRLDLPT
GDGQPSLEPP MAFGAPGIIS SPYAGAAGFA PAIGFPQATG LSVPAGLGPG ALGPLAITSS
AVTGRMAIPG AGGIPGNSVL LVTNLNPDLI TPHGLFILFG VYGDVHRVKI MFNKKENALV
QMADANQAQL AMNHLSGQRL YGKVLRATLS KHQAVQLPRE GQEDQGLTKD FSNSPLHRFK
KPGSKNFQNI FPPSATLHLS NIPPSVTVDD LKNLFTETGC SVKAFKFFQK DRKMALIQLG
SVEEAIQALI ELHNHDLGEN HHLRVSFSKS TI
//
