ID   A0A2Y9F286_PHYMC        Unreviewed;      1324 AA.
AC   A0A2Y9F286;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Fanconi anemia group I protein isoform X6 {ECO:0000313|RefSeq:XP_007113570.2};
GN   Name=FANCI {ECO:0000313|RefSeq:XP_007113570.2};
OS   Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Physeteridae; Physeter.
OX   NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007113570.2};
RN   [1] {ECO:0000313|RefSeq:XP_007113570.2}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_007113570.2};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   RefSeq; XP_007113570.2; XM_007113508.4.
DR   Proteomes; UP000248484; Chromosome 11.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   CDD; cd11720; FANCI; 1.
DR   InterPro; IPR026171; FANCI.
DR   InterPro; IPR029310; FANCI_HD1.
DR   InterPro; IPR029312; FANCI_HD2.
DR   InterPro; IPR029308; FANCI_S1.
DR   InterPro; IPR029305; FANCI_S1-cap.
DR   InterPro; IPR029315; FANCI_S2.
DR   InterPro; IPR029313; FANCI_S3.
DR   InterPro; IPR029314; FANCI_S4.
DR   PANTHER; PTHR21818; BC025462 PROTEIN; 1.
DR   PANTHER; PTHR21818:SF0; FANCONI ANEMIA GROUP I PROTEIN; 1.
DR   Pfam; PF14679; FANCI_HD1; 1.
DR   Pfam; PF14680; FANCI_HD2; 1.
DR   Pfam; PF14675; FANCI_S1; 1.
DR   Pfam; PF14674; FANCI_S1-cap; 1.
DR   Pfam; PF14676; FANCI_S2; 1.
DR   Pfam; PF14677; FANCI_S3; 1.
DR   Pfam; PF14678; FANCI_S4; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000248484}.
FT   DOMAIN          1..53
FT                   /note="FANCI solenoid 1 cap"
FT                   /evidence="ECO:0000259|Pfam:PF14674"
FT   DOMAIN          64..280
FT                   /note="FANCI solenoid 1"
FT                   /evidence="ECO:0000259|Pfam:PF14675"
FT   DOMAIN          284..370
FT                   /note="FANCI helical"
FT                   /evidence="ECO:0000259|Pfam:PF14679"
FT   DOMAIN          378..541
FT                   /note="FANCI solenoid 2"
FT                   /evidence="ECO:0000259|Pfam:PF14676"
FT   DOMAIN          555..784
FT                   /note="FANCI helical"
FT                   /evidence="ECO:0000259|Pfam:PF14680"
FT   DOMAIN          803..1028
FT                   /note="FANCI solenoid 3"
FT                   /evidence="ECO:0000259|Pfam:PF14677"
FT   DOMAIN          1041..1290
FT                   /note="FANCI solenoid 4"
FT                   /evidence="ECO:0000259|Pfam:PF14678"
FT   REGION          1216..1235
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1297..1324
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1324 AA;  149050 MW;  44135CCA1EB2B0D0 CRC64;
     MDQKILSLAA EKTADRLQKF LQTLKEDDLA NLLQNQAVKG KAAGALLRAI FKGFPCSEEA
     GALRRLKIYS CCVQLLESGD LQKEVASEII GFLMLEVHSF PGALLVELAN EFVDAIKEGN
     LMNGKSLELL PIIFTALATK TENLAYGKGE LSGEECKKQL INTLCSGRWD HQYVIQLTSM
     FKDVPLTAEE VEIVVEKVLT MFSKLNLQEI PPLVCQLLVL SSKGSRKRVL EGIIAFFNKL
     DKQHSEEQSG DELLDFVTVP SGELRHVEGT IILHIVFAIK LDCELGRELL KLLKAGQQGD
     FSSNICPFSI ALFLSVTRIQ RFEEQVFDLL KSLVIKSFKD LQLLQGSKFL QNLVPHRCCV
     STMILEVVKN SVHSWDHVTQ GLVELGFILM DSYGPKKIPD GKTIEASSGL SRMPNQHACK
     LGANILLETF KIHEMIRQEI LEQVLNRVVT RGSSPITHFI DLLSNIIMYS PLVLQSCSSK
     VTETFDYLSF LPLQTVQGLL KAVQPLLKVS LSVRDSLILV LRKAMFASQL DARKSAVAGF
     LLLLKNFKVL GSLSSSQCSQ SIGISQVHVD VHSRYNSVAN ETFCLEIMDS LRRCLGQQAD
     VRLMLYEGFY DVLRRNSQLA NSIMQTLLSQ LKQFYEPEPD VLPPLKLEAC ILTQGDQISL
     QEPLDCLLCC IQHCLAWYKS RVVPLQQKEE EEEEEGFYQD LDDMLESITS RMIKSELEDF
     ELDKSADFSQ NTGIGIKNNI CAFLVMGVCE VLIEYNFSIS NFSKNKFEEV LSLFMCYKEL
     SDILNEKTGK GKTKMANKTN DSFLSMKFVS DLLTALFRDS TQSHEESLSV LRSSNDFMRY
     AVSVALQKVQ QLKETGHVSG PDGQNPEKVF QNLCDITRVL LWRYTSIPTS VEESGKKEKG
     KSISLLCLEG LQKIFSAVQQ FYQPKIHQFL RALDATDKEE EEVEVSVTQR AAFQIRQFQR
     SLLNILSSQE EDFNSKEALL LVTVLSNLSK LLEPSSTQFV QMLSWTTEIC KENSWEDASF
     CKGLMNLLFS LHVLCKSPVT LLRDLSQDIH GHLGDIDQDV EVEKTNHFAM VNLRTAAPTV
     CLLLLSQAER VLEEVDWLIT KLKGQVSQEI IPEASSQATL PNHPIEKAII IQLGTLLTFF
     HELVQTALPS GSCVDTLLKD LCKMYTILTA LVRYYLQVCQ HSRGIPKNME KLVKLSGSHL
     TPLCYSFISY IQNKKSKSPK HTGEKKKEKT AAGPTAMARA LRETKPIPNL IFAIEQYEKF
     LIHLSKRSKV NLMQHIKLST SRDFKIKGNV LDMVLQEDED EDEEGTASEL EGQNKEPAKK
     KRKK
//