ID   A0A2Y9F2P6_PHYMC        Unreviewed;       507 AA.
AC   A0A2Y9F2P6;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Enhancer of mRNA-decapping protein 3 {ECO:0000256|ARBA:ARBA00015797};
DE   AltName: Full=YjeF domain-containing protein 1 {ECO:0000256|ARBA:ARBA00032192};
GN   Name=EDC3 {ECO:0000313|RefSeq:XP_007113813.1,
GN   ECO:0000313|RefSeq:XP_028350857.1, ECO:0000313|RefSeq:XP_054944093.1};
OS   Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Physeteridae; Physeter.
OX   NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007113813.1};
RN   [1] {ECO:0000313|RefSeq:XP_007113813.1, ECO:0000313|RefSeq:XP_028350857.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_007113813.1,
RC   ECO:0000313|RefSeq:XP_028350857.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC       {ECO:0000256|ARBA:ARBA00004201}.
CC   -!- SIMILARITY: Belongs to the EDC3 family.
CC       {ECO:0000256|ARBA:ARBA00006610}.
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DR   RefSeq; XP_007113813.1; XM_007113751.4.
DR   RefSeq; XP_007113814.1; XM_007113752.1.
DR   RefSeq; XP_028350857.1; XM_028495056.2.
DR   RefSeq; XP_054944093.1; XM_055088118.1.
DR   STRING; 9755.ENSPCTP00005022311; -.
DR   Ensembl; ENSPCTT00005024577; ENSPCTP00005022311; ENSPCTG00005015986.
DR   GeneID; 102980939; -.
DR   KEGG; pcad:102980939; -.
DR   CTD; 80153; -.
DR   OrthoDB; 4100524at2759; -.
DR   Proteomes; UP000248484; Chromosome 11.
DR   GO; GO:0000932; C:P-body; IEA:UniProtKB-SubCell.
DR   GO; GO:0042802; F:identical protein binding; IEA:Ensembl.
DR   GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR   GO; GO:0031087; P:deadenylation-independent decapping of nuclear-transcribed mRNA; IEA:InterPro.
DR   CDD; cd01737; LSm16_N; 1.
DR   Gene3D; 2.30.30.100; -; 1.
DR   Gene3D; 3.40.50.10260; YjeF N-terminal domain; 1.
DR   InterPro; IPR025762; DFDF.
DR   InterPro; IPR019050; FDF_dom.
DR   InterPro; IPR025609; Lsm14-like_N.
DR   InterPro; IPR034107; Lsm16_N.
DR   InterPro; IPR047575; Sm.
DR   InterPro; IPR004443; YjeF_N_dom.
DR   InterPro; IPR036652; YjeF_N_dom_sf.
DR   PANTHER; PTHR13612:SF0; ENHANCER OF MRNA-DECAPPING PROTEIN 3; 1.
DR   PANTHER; PTHR13612; UNCHARACTERIZED; 1.
DR   Pfam; PF16598; Edc3_linker; 1.
DR   Pfam; PF09532; FDF; 1.
DR   Pfam; PF12701; LSM14; 1.
DR   Pfam; PF03853; YjeF_N; 1.
DR   SMART; SM01199; FDF; 1.
DR   SMART; SM01271; LSM14; 1.
DR   SUPFAM; SSF64153; YjeF N-terminal domain-like; 1.
DR   PROSITE; PS51512; DFDF; 1.
DR   PROSITE; PS52002; SM; 1.
DR   PROSITE; PS51385; YJEF_N; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248484}.
FT   DOMAIN          1..68
FT                   /note="Sm"
FT                   /evidence="ECO:0000259|PROSITE:PS52002"
FT   DOMAIN          191..227
FT                   /note="DFDF"
FT                   /evidence="ECO:0000259|PROSITE:PS51512"
FT   DOMAIN          282..486
FT                   /note="YjeF N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51385"
FT   REGION          101..190
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        103..147
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        154..179
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   507 AA;  55906 MW;  D736DE3E7BA28158 CRC64;
     MATDWLGSIV SINCGDSLGV YQGRVSAVDQ VSQTISLTRP FHNGVKCLVP EVTFRAGDIT
     ELKILEIPGP GENQHFGDLH QTELGPSGVG CQVGINQNGM GKLVKKPASS SSAPQNIPKR
     TDVKSQDVAV SPQQQCSKSY VDRHMESLSQ SKSFRRRHNS WSSSSRHPNQ ATPKKSGLKN
     GQMKNKDDEC FGDDIEEIPD TDFDFEGNLA LFDKAAVFEE IDTYERRSGT RSRGIPNERP
     TRYRHDENIL ESEPIVYRRI TVPHNVSKEF CTDSGLVVPS ISYELHKKLL SVAEKHGLTL
     ERRLEMTGVC ASQMALTLLG GPNRLNPKNV HQRPTVALLC GPHVKGAQGI SCGRHLANHD
     VQVILFLPNF VKMLESITNE LSLFSKTQGQ QVSSLKDLPT SPVDLVINCL DCPENAFLRD
     QPWYKAAVAW ANQNRAPVLS IDPPVHEVEQ GIDAKWSLAL GLPLPLGEHA GRVYLCDIGI
     PQQVFQEVGI SYHSPFGCKF VIPLHSA
//