ID A0A2Y9F2X9_PHYMC Unreviewed; 168 AA.
AC A0A2Y9F2X9;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=D-aminoacyl-tRNA deacylase {ECO:0000256|ARBA:ARBA00013056};
DE EC=3.1.1.96 {ECO:0000256|ARBA:ARBA00013056};
GN Name=DTD2 {ECO:0000313|RefSeq:XP_007113421.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007113421.1};
RN [1] {ECO:0000313|RefSeq:XP_007113421.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007113421.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA +
CC H(+); Xref=Rhea:RHEA:13953, Rhea:RHEA-COMP:10123, Rhea:RHEA-
CC COMP:10124, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:59871,
CC ChEBI:CHEBI:78442, ChEBI:CHEBI:79333; EC=3.1.1.96;
CC Evidence={ECO:0000256|ARBA:ARBA00033671};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=glycyl-tRNA(Ala) + H2O = glycine + H(+) + tRNA(Ala);
CC Xref=Rhea:RHEA:53744, Rhea:RHEA-COMP:9657, Rhea:RHEA-COMP:13640,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:57305,
CC ChEBI:CHEBI:78442, ChEBI:CHEBI:78522; EC=3.1.1.96;
CC Evidence={ECO:0000256|ARBA:ARBA00000741};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_007113421.1; XM_007113359.4.
DR AlphaFoldDB; A0A2Y9F2X9; -.
DR STRING; 9755.ENSPCTP00005010294; -.
DR Ensembl; ENSPCTT00005011405; ENSPCTP00005010294; ENSPCTG00005007351.
DR GeneID; 102982981; -.
DR KEGG; pcad:102982981; -.
DR CTD; 112487; -.
DR InParanoid; A0A2Y9F2X9; -.
DR OrthoDB; 3015787at2759; -.
DR Proteomes; UP000248484; Chromosome 11.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0106105; F:Ala-tRNA(Thr) hydrolase activity; IEA:Ensembl.
DR GO; GO:0051500; F:D-tyrosyl-tRNA(Tyr) deacylase activity; IEA:Ensembl.
DR Gene3D; 3.50.80.10; D-tyrosyl-tRNA(Tyr) deacylase; 1.
DR InterPro; IPR003732; Daa-tRNA_deacyls_DTD.
DR InterPro; IPR023509; DTD-like_sf.
DR PANTHER; PTHR10472:SF1; D-AMINOACYL-TRNA DEACYLASE 2; 1.
DR PANTHER; PTHR10472; D-TYROSYL-TRNA TYR DEACYLASE; 1.
DR Pfam; PF02580; Tyr_Deacylase; 1.
DR SUPFAM; SSF69500; DTD-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000248484}.
SQ SEQUENCE 168 AA; 18501 MW; E1EDB1A7B8F650BA CRC64;
MDESGRPPQA RALLQQCLHA RLQVRPAEGD AAAQWVEVQR GLVIYVCFFK GADKELLPKM
VNTLLNVKLS ETENGKHVSV LDLPGNILII PQATLGGRVK GRSMQYHSNS GKEEGLELYS
QFVTLCKKEL AANSKCAEAG VVVEHGTYGN RQVLKLDTNG PYTHLIEF
//
