ID A0A2Y9FBA3_PHYMC Unreviewed; 2362 AA.
AC A0A2Y9FBA3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Nucleoprotein TPR {ECO:0000256|ARBA:ARBA00019789};
GN Name=TPR {ECO:0000313|RefSeq:XP_007117811.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007117811.1};
RN [1] {ECO:0000313|RefSeq:XP_007117811.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007117811.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TPR family. {ECO:0000256|ARBA:ARBA00005274}.
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DR RefSeq; XP_007117811.1; XM_007117749.4.
DR STRING; 9755.ENSPCTP00005004490; -.
DR GeneID; 102993712; -.
DR KEGG; pcad:102993712; -.
DR CTD; 7175; -.
DR InParanoid; A0A2Y9FBA3; -.
DR OrthoDB; 3135837at2759; -.
DR Proteomes; UP000248484; Chromosome 4.
DR GO; GO:0034399; C:nuclear periphery; IEA:UniProt.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProt.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.10.287.1490; -; 2.
DR InterPro; IPR012929; TPR/MLP1.
DR PANTHER; PTHR18898:SF2; NUCLEOPROTEIN TPR; 1.
DR PANTHER; PTHR18898; NUCLEOPROTEIN TPR-RELATED; 1.
DR Pfam; PF07926; TPR_MLP1_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484}.
FT DOMAIN 1039..1166
FT /note="Nucleoprotein TPR/MLP1"
FT /evidence="ECO:0000259|Pfam:PF07926"
FT REGION 633..655
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 915..935
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1454..1474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1619..1674
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1803..2124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2226..2362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 29..172
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 212..281
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 321..366
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 427..513
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 543..603
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 665..801
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1096..1176
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1221..1416
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1619..1636
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1637..1674
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1803..1827
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1880..1898
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1905..1937
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1944..1984
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1999..2013
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2020..2069
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2070..2089
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2226..2259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2295..2324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2362 AA; 267258 MW; FF86313279DB0BA2 CRC64;
MAAVLQQVLE RTELNKLPKS VQNKLEKFLA DQQSEIDGLK GRHEKFKVES EQQYFEIEKR
LSHSQERLVN ETRECQSLRL ELEKLNSQLK VLTEKNKELE VAQDRNIAIQ SQFTRTKEEL
EAEKRDLIRT NERLSQELEY LTEDVKRLNE KLKESNATKG ELQLKLDELQ ASDVSVKYRE
KRLEQEKELL HNQNTWLNTE LKTKTDELLA LSRDKGNEIL ELKCNLENKK EEVSRMEEQM
NGLKTSNENL QKHVEDLLTK LKEAKEQQAS MEEKFHNELN AHIKLSNLYK SAADDSEAKS
NELTRAVDEL HKLLKEAGEA NKAIQDHLLE VEESKDQMEK EMLEKIGKLE KELENANDLL
SATKRKGAIL SEEELAAMSP TAAAVAKIVK PGMKLTELYN AYVETQDQLL LEKLENKRIN
KYLDEIVKEV EAKAPILKRQ REEYERAQKA VASLSVKLEQ AMKEIQRLQE DTDKANKHSS
VLERDNQRME VQIKDLSQQI RVLLMELEEA RGNHVIRDEE VSSADISSSS EVISQHLVSY
RNIEELQQQN QRLLVALREL GETREREEQE TTSSKITELQ LKLESALAEL EQLRESRRHQ
MQLVDSIVRQ RDMYRILLSQ TTGVTIPLQA SSLDDSSLVS TPKRSSTSQT VSTPTPVPVI
ESAEAIEAKA ALKQLQEIFE NYRKEKADNE KMQNEQLEKL QEQVTDLRSQ NTKISTQLDF
ASKRYEMLQD NVEGYRREIT SLHERNQKLT AATQKQEQII NTMTQDLRGA SEKLAVAEVR
AENLKKEKEM LKLSEVRLSQ QRESLLAEQR GQNLLLTNLQ TIQGILERSE TETKQRLSSQ
IEKLEHEISH LKKKLENEVE QRHTLTRNLD VQLLDTKRQL DTETNLHLNT KELLKNAQKE
IATLKQHLSN VEVQLASQSS QRTGKGQPSN KEDVDDLLSQ LRQAEEQVND LKERLKTSTS
NVEQYRAMVT SLEESLNKEK QVTEEVHKNI EVRLKESAEF QTQLEKKLME VEKEKQELQD
DKRKAIESME QQLSELKKTL NSVQNEVQEA LQRAGTALSN EQQARRDCQE QAKIAVEAQN
KYERELMLHA ADVEALQAAK EQVSKMVSVR QHLEETTQKA ESQLLECKAS WEERERMLKD
EVSKSMSRCE DLEKQNRLLH DQIEKLSDKV VAAMKEGVQG PLNVSLSEEG KSQEQILEIL
RFIRREKEIA ETRFEVAQVE SLRYRQRVEL LERELQELQD SLNAEREKVQ VTAKTMAQHE
ELMKKTETMN VVMETNKMLR EEKERLEQDL QQMQAKVRKL ELDILPLQEA NAELSEKSGM
LQAEKKLLEE DVKRWKARNQ HLVSQQKDPD TEEYRKLLSE KEVQAKRIQQ LTEETGRLKA
EIARSNASLT NNQNLIQSLK EDLNKVKTEK ESIQKDLDAK IIDIQEKVKT ITQVKKIGRR
YKTQYEELKA QQDKVMETSA QSSGDHQEQH VSVQEMQELK ETLNQAETKS KSLESQVENL
QKTLSEKEME ARNLQEQTVQ LQSELSRLRQ DLQDRTTQEE QLRQQITEKE EKTRKAIVAA
KSKIAHLAGV KDQLTKENEE LKQRNGALDQ QKDELDVRMT ALKSQYEGRI SRLERELREH
QERHLEQRDE PQEPTNKVPE QQRQITLKTA PTSGERGIAS TSDPPTANIK PTPVVSTPSK
VTAAAMAGNK STPRASIRPM VTPATVTNPT TTPTATVMPT TQVESQEAMQ SEGPVEHVPV
FGSTSGSVRS TSPNVQPSIP QPILTVQQQT QATAFVQPTQ QSHPQIEPTN QELSPNIVEV
VQSSPVERPS TSTAVFGTVS ATPSSSLPKR TREEEEDSTI EASDQISDDT VEMPLPKKLK
SVTPVGTEEE VMAEESTDGE VETQVYNQDS QDSIGEGVTQ GDYTPMEDSE ETSQSLQIDL
GPLQSDQQTT SSQDGQGKGD DVIVIDSDDE EEDDDENDGE HEDYEEDEEE DDDDEDDTGM
GDEGEDSNEG TGSADGNDGY EADDAEGGDG TDPGTETEES MGGGESNQRA ADSQNSGEGN
TGTAESSFSQ EISREQQPSS ASERQTPRAP QSPRRPPHPL PPRLTIHAPP QELGPPVQRI
QMTRRQSVGR GLQLTPGIGG MQQHFFDDED RTVPSTPTLV VPHRTDGFAE AIHSPQVAGV
PRFRFGPPED MPQTSSSHSD LGQLASQGGL GMYETPLFLA HEEESGGRSV PTTPLQVAAP
VTVFTESTTS DASEHASQSV PMVTTSTGTL STTNETATGD DGDEVFVEAE SEGISSEAGL
EIDSQQEEEP VQASDESDLP STSQDPPSSS SVDTSSSQPK PFRRVRLQTT LRQGVRGRQF
NRQRGVSHAM GGRGGINRGN IN
//
