ID A0A2Y9FBD3_PHYMC Unreviewed; 428 AA.
AC A0A2Y9FBD3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=SH3 domain-containing kinase-binding protein 1 isoform X9 {ECO:0000313|RefSeq:XP_007119024.1};
GN Name=SH3KBP1 {ECO:0000313|RefSeq:XP_007119024.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007119024.1};
RN [1] {ECO:0000313|RefSeq:XP_007119024.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007119024.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007119024.1; XM_007118962.4.
DR AlphaFoldDB; A0A2Y9FBD3; -.
DR GeneID; 102977116; -.
DR KEGG; pcad:102977116; -.
DR CTD; 30011; -.
DR OrthoDB; 2972088at2759; -.
DR Proteomes; UP000248484; Chromosome 21.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd12057; SH3_CIN85_3; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR035772; CIN85_SH3_3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR14167; SH3 DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR14167:SF6; SH3 DOMAIN-CONTAINING KINASE-BINDING PROTEIN 1; 1.
DR Pfam; PF14604; SH3_9; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR PRINTS; PR01887; SPECTRNALPHA.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000313|RefSeq:XP_007119024.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443};
KW Transferase {ECO:0000313|RefSeq:XP_007119024.1}.
FT DOMAIN 33..90
FT /note="SH3"
FT /evidence="ECO:0000259|SMART:SM00326"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 91..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 230..370
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 372..417
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 116..153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 272..294
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 428 AA; 46662 MW; EA207202012723B2 CRC64;
MMGEETIGKK LPPTAATPDS SKTEMDSRTK AKDYCKVIFP YEAQNDDELT IKEGDIVTLI
NKDCIDVGWW EGELNGRRGV FPDNFVKLLP PDFEKEGNRP KKPPPPSAPV IKQGAGTTER
KHEIKKIPPE RPETLPNRTE EKERPEREPK LDLQKPSVPA IPPKKPRPPK TNSLSRPGAL
PPRRPERPAG PLTHTRGDGP KIDLAGSSIS GILDKDLSDR SNDIDLEGFD SVVSSTEKLS
HPTTSRPKAT GRRPPSQSLT SSSLSSPDIF DSPSPEEDKE EHVSLAHRGA DASKKTSKTV
TISQVSDNKA SLPPKPGTMA AGSGGPAPLS SAASSPLSSS LGTVGHRANS PSLFGAEGKP
KMEPPASSQA AVEELRTQVR ELRNIIETMK DQQKREIKQL LSELDEEKKI RLRLQMEVND
IKKALQSK
//
