ID A0A2Y9FBL3_PHYMC Unreviewed; 666 AA.
AC A0A2Y9FBL3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Zinc finger protein 599 {ECO:0000313|RefSeq:XP_007119036.1};
GN Name=ZNF599 {ECO:0000313|RefSeq:XP_007119036.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007119036.1};
RN [1] {ECO:0000313|RefSeq:XP_007119036.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007119036.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_007119036.1; XM_007118974.4.
DR AlphaFoldDB; A0A2Y9FBL3; -.
DR Ensembl; ENSPCTT00005019525; ENSPCTP00005017705; ENSPCTG00005012568.
DR GeneID; 102981517; -.
DR KEGG; pcad:102981517; -.
DR CTD; 148103; -.
DR InParanoid; A0A2Y9FBL3; -.
DR OrthoDB; 5250644at2759; -.
DR Proteomes; UP000248484; Chromosome 17.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 14.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24381; ZINC FINGER PROTEIN; 1.
DR PANTHER; PTHR24381:SF154; ZINC FINGER PROTEIN 550; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 14.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 14.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 8.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 14.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 279..299
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT DOMAIN 307..327
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT DOMAIN 335..355
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT DOMAIN 363..383
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT DOMAIN 391..411
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT DOMAIN 419..439
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT DOMAIN 447..467
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT DOMAIN 475..495
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT DOMAIN 503..523
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT DOMAIN 531..551
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT DOMAIN 559..579
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT DOMAIN 587..607
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT DOMAIN 615..635
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT DOMAIN 643..663
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS00028"
FT REGION 18..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 184..222
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..222
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 666 AA; 75828 MW; E04F50F263A81C6C CRC64;
MSRDPPLERV VSRALSELGP SFRSPQVPEA APGALYASHT ADTQVPCAPA QGWPEESAEP
AGPAFVAASR RPALPTGPMA ALELALVSFE DVAVTFTGEE WRHLDLAQRT LYQEVMLETC
GLLVSLGHPV PKPELIPLLE HGQELRTVKR GLSRSTCTGE KAKPEITELT ASQLVLTEGA
PFEERVTHGA SRHSRLEQAR DQEKLSEMQE GNLRPGTDIH KETCPRKLSH KHDDFETDDS
LYLRVLQERV TTRDALHERD SQEPGGDPVI DARNNLYKCK ECGKGFSKNW ALVRHQQIHA
GVKPYECSEC GKACRYMADF IRHMRFHTGE KPYKCIECGK AFKRRSHLTE HQRIHTGDKP
YECKECGKAF THRSSFIQHN MTHTREKPFL CKECGKAFYY SSSFAQHMRI HTGKKLYKCS
ECGKAFTHRS TFIQHNMTHT GEKPFLCKEC GKAFCLNSSF TQHMRIHTGE KPYECSECGR
AFTHRSTFIR HKRTHTGEKP FECKECGKAF CDSSSLIQHM RIHTGERPYE CSECGKAFTH
HSVFIRHNKT HSGEKPLECK ECAKAFYYSS SFTRHMRIHT GEKPYVCREC GKAFTQPANF
VRHNRIHTGE KPYECKECEK AFCDNFALTQ HMRTHTGEKP FECGECGKAF SHSSSFIHHR
KIHTRV
//
