ID A0A2Y9FCY3_PHYMC Unreviewed; 240 AA.
AC A0A2Y9FCY3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Synaptophysin-like protein 1 {ECO:0000313|RefSeq:XP_007120128.1};
GN Name=SYPL1 {ECO:0000313|RefSeq:XP_007120128.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007120128.1};
RN [1] {ECO:0000313|RefSeq:XP_007120128.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007120128.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the synaptophysin/synaptobrevin family.
CC {ECO:0000256|ARBA:ARBA00006476}.
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DR RefSeq; XP_007120128.1; XM_007120066.4.
DR AlphaFoldDB; A0A2Y9FCY3; -.
DR STRING; 9755.ENSPCTP00005004607; -.
DR Ensembl; ENSPCTT00005005093; ENSPCTP00005004624; ENSPCTG00005003285.
DR GeneID; 102976932; -.
DR KEGG; pcad:102976932; -.
DR CTD; 6856; -.
DR InParanoid; A0A2Y9FCY3; -.
DR OrthoDB; 2881347at2759; -.
DR Proteomes; UP000248484; Chromosome 5.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008021; C:synaptic vesicle; IEA:InterPro.
DR InterPro; IPR008253; Marvel.
DR InterPro; IPR001285; Synaptophysin/porin.
DR PANTHER; PTHR10306; SYNAPTOPHYSIN; 1.
DR PANTHER; PTHR10306:SF9; SYNAPTOPHYSIN-LIKE PROTEIN 1; 1.
DR Pfam; PF01284; MARVEL; 1.
DR PRINTS; PR00220; SYNAPTOPHYSN.
DR PROSITE; PS51225; MARVEL; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|PROSITE-ProRule:PRU00581, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Transmembrane {ECO:0000256|PROSITE-ProRule:PRU00581,
KW ECO:0000256|SAM:Phobius}; Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 98..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 10..218
FT /note="MARVEL"
FT /evidence="ECO:0000259|PROSITE:PS51225"
FT REGION 221..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 240 AA; 26386 MW; C2B37F060CD67D4A CRC64;
MSSFQLNLNP LKEPLGFIKV LEWIASIFAF ATCGGFKGKT EIQVACHTNP DNKTITATFG
YPFRLNEASF QPPQGVNVCG VDWESHVLIG DYSSSAQFYV TFAVFVFLYC IAALLLYVGY
TNLYRDSRKL PMVDFVITLV ATFLWLVSTS AWAKALTDIK TATGRNIVQE LPPCKQPEVI
CHFGSVTSMG SLNVSVIFGF LNMILWGGNA WFVYKETSLH SPSNTSTSHS QGGIPPPTGI
//
