ID A0A2Y9FDK2_PHYMC Unreviewed; 232 AA.
AC A0A2Y9FDK2;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Replication factor A protein 2 {ECO:0000256|ARBA:ARBA00043137};
GN Name=RPA2 {ECO:0000313|RefSeq:XP_007120404.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007120404.1};
RN [1] {ECO:0000313|RefSeq:XP_007120404.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007120404.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the replication factor A protein 2 family.
CC {ECO:0000256|ARBA:ARBA00007815}.
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DR RefSeq; XP_007120404.1; XM_007120342.4.
DR AlphaFoldDB; A0A2Y9FDK2; -.
DR GeneID; 102973407; -.
DR CTD; 6118; -.
DR OrthoDB; 72010at2759; -.
DR Proteomes; UP000248484; Chromosome 3.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031090; C:organelle membrane; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd04478; RPA2_DBD_D; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR040260; RFA2-like.
DR InterPro; IPR014646; Rfa2/RPA32.
DR InterPro; IPR014892; RPA_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR13989:SF16; REPLICATION PROTEIN A 32 KDA SUBUNIT; 1.
DR PANTHER; PTHR13989; REPLICATION PROTEIN A-RELATED; 1.
DR Pfam; PF08784; RPA_C; 1.
DR PIRSF; PIRSF036949; RPA32; 2.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000248484}.
FT DOMAIN 128..224
FT /note="Replication protein A C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08784"
FT REGION 20..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..37
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 232 AA; 25001 MW; 0068F24ECE104CDA CRC64;
MWTSGFESYS SSSFGGAGGY TQSPGGFGSP TPSQAEKKSR ARAQHIVPCT ISQLLSATLV
DEVFKIGNVE ISQDASSENT VVPPETYVKV AGHLRSFQNK KSLVAFKIMP LEDMNEFTTH
ILEVVNAHMM LSKSNSQPSA GRAPISNPGM GEAGNFGGNS FMPANGLNMA QNQVLNLIKA
CPRPEGLNFQ DLKNQLQHMT VASIKQAVDF LSNEGHIYST VDDDHFKSTD AE
//
