ID A0A2Y9FDV7_PHYMC Unreviewed; 362 AA.
AC A0A2Y9FDV7;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Microfibril-associated glycoprotein 3 {ECO:0000313|RefSeq:XP_007119410.1, ECO:0000313|RefSeq:XP_007119411.1};
GN Name=MFAP3 {ECO:0000313|RefSeq:XP_007119410.1,
GN ECO:0000313|RefSeq:XP_007119411.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007119411.1};
RN [1] {ECO:0000313|RefSeq:XP_007119410.1, ECO:0000313|RefSeq:XP_007119411.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007119410.1,
RC ECO:0000313|RefSeq:XP_007119411.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane
CC protein {ECO:0000256|ARBA:ARBA00004479}.
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DR RefSeq; XP_007119410.1; XM_007119348.4.
DR RefSeq; XP_007119411.1; XM_007119349.4.
DR STRING; 9755.ENSPCTP00005002290; -.
DR Ensembl; ENSPCTT00005002517; ENSPCTP00005002290; ENSPCTG00005001678.
DR GeneID; 102982539; -.
DR KEGG; pcad:102982539; -.
DR CTD; 4238; -.
DR OrthoDB; 3023373at2759; -.
DR Proteomes; UP000248484; Chromosome 8.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013151; Immunoglobulin.
DR PANTHER; PTHR11422:SF9; MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3; 1.
DR PANTHER; PTHR11422; T-CELL SURFACE GLYCOPROTEIN CD4; 1.
DR Pfam; PF00047; ig; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..362
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041069091"
FT TRANSMEM 149..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 46..137
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 282..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..362
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 362 AA; 40000 MW; C5EDA269527E925E CRC64;
MKPHCCLFTL VVSVTVPAAF ALEDVGFNQM TPLGANHSSS NASFLPSFEL SADSHSGDDV
IIAREGTSVS IECLLTVDHY EGVYWYNSKG QQLDNRGRGG KWLVSDNFLN ITNVAFADRG
LYTCFITSPI RASYSVTLRV IFTSGDMSVY YMVVCLIAFT ITLILNVTRL CMMSSHLRKT
EKAINEFFRT EGAEKLQKAF EIAKRIPIIT SAKTLELAKV TQFKTMEFAR YIEELARSVP
LPPLILNCRA FVEEMFEAVR VDDPDDMGER IKERPALNGQ DGIFVINPEM GRSNSPGGDS
DDGSLSEQGQ EIAVQVSVHL QSETKSIDTD SQDSSHFSPP DDTGSAELNS NYKDGAYESC
QL
//
