ID A0A2Y9FE47_PHYMC Unreviewed; 485 AA.
AC A0A2Y9FE47;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Probable RNA-binding protein 46 {ECO:0000256|ARBA:ARBA00021018};
DE AltName: Full=RNA-binding motif protein 46 {ECO:0000256|ARBA:ARBA00030581};
GN Name=RBM46 {ECO:0000313|RefSeq:XP_007119546.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007119546.1};
RN [1] {ECO:0000313|RefSeq:XP_007119546.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007119546.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR RefSeq; XP_007119546.1; XM_007119484.3.
DR AlphaFoldDB; A0A2Y9FE47; -.
DR STRING; 9755.ENSPCTP00005004962; -.
DR Ensembl; ENSPCTT00005005461; ENSPCTP00005004962; ENSPCTG00005003497.
DR GeneID; 102979083; -.
DR KEGG; pcad:102979083; -.
DR CTD; 166863; -.
DR OrthoDB; 3184171at2759; -.
DR Proteomes; UP000248484; Chromosome 7.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd19901; DSRM_RBM46; 1.
DR CDD; cd12484; RRM1_RBM46; 1.
DR CDD; cd12492; RRM2_RBM46; 1.
DR CDD; cd12496; RRM3_RBM46; 1.
DR Gene3D; 3.30.70.330; -; 3.
DR InterPro; IPR006535; HnRNP_R/Q_splicing_fac.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR044462; RBM46_DSR.
DR InterPro; IPR034434; RBM46_RRM1.
DR InterPro; IPR034435; RBM46_RRM2.
DR InterPro; IPR047837; RBM46_RRM3.
DR InterPro; IPR000504; RRM_dom.
DR NCBIfam; TIGR01648; hnRNP-R-Q; 1.
DR PANTHER; PTHR21245; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; 1.
DR PANTHER; PTHR21245:SF3; RNA-BINDING PROTEIN 46-RELATED; 1.
DR Pfam; PF14709; DND1_DSRM; 1.
DR Pfam; PF00076; RRM_1; 3.
DR SMART; SM00360; RRM; 3.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR PROSITE; PS50102; RRM; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}.
FT DOMAIN 61..139
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 141..223
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 236..308
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT REGION 342..362
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 485 AA; 55243 MW; FEB47133AA5B43B3 CRC64;
MNEENTDGTN GCSKVRTGTQ NEAALLALME KTGYNMVQEN GQRKFGGPPP GWEGPPPPRG
CEVFVGKIPR DMYEDELVPV FERAGKIYEF RLMMEFSGEN RGYAFVMYTT KEEAQLAIRI
LNNYEIRPGK FIGVCVSLDN CRLFIGAIPK EKKKEEILDE MKKVTEGVID VIVYPSATDK
TKNRGFAFVE YESHRAAAMA RRKLIPGTFQ LWGHTIQVDW ADPEKEVDEE TMQRVKVLYV
RNLMISTTEE TIKVEFNKFK PGAVERVKKL RDYAFVHFFN REDAVAAMSV MNGKCIDGAS
IEVTLAKPVN KENTWRQHLN GQISPNSENL IVFANKEESH PKTLGKPPTL PARLNGQHSP
SPPEIERCTY PFFPGTKLTP ISMYSLKSSH FNSAVMHLDY YCNKNNWAPP EYYLYSTTSQ
DGKVLLVYKI IIPAIANGSQ SYFMPDKLCT TLEDAKELAA QFTLLHLDRE HSLFSLDLCR
RIWRK
//
