ID A0A2Y9FGF7_PHYMC Unreviewed; 764 AA.
AC A0A2Y9FGF7;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Protein Jade-1 {ECO:0000256|ARBA:ARBA00040212};
DE AltName: Full=Jade family PHD finger protein 1 {ECO:0000256|ARBA:ARBA00041998};
DE AltName: Full=PHD finger protein 17 {ECO:0000256|ARBA:ARBA00042970};
GN Name=JADE1 {ECO:0000313|RefSeq:XP_028348101.1,
GN ECO:0000313|RefSeq:XP_028348102.1, ECO:0000313|RefSeq:XP_028348103.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_028348102.1};
RN [1] {ECO:0000313|RefSeq:XP_028348101.1, ECO:0000313|RefSeq:XP_028348102.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_028348101.1,
RC ECO:0000313|RefSeq:XP_028348102.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium basal body
CC {ECO:0000256|ARBA:ARBA00004120}.
CC -!- SIMILARITY: Belongs to the JADE family.
CC {ECO:0000256|ARBA:ARBA00038371}.
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DR RefSeq; XP_007121027.1; XM_007120965.1.
DR RefSeq; XP_007121028.1; XM_007120966.1.
DR RefSeq; XP_028348101.1; XM_028492300.2.
DR RefSeq; XP_028348102.1; XM_028492301.2.
DR RefSeq; XP_028348103.1; XM_028492302.2.
DR Proteomes; UP000248484; Chromosome 7.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15704; ePHD_JADE1; 1.
DR CDD; cd15679; PHD_JADE1; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR039546; Jade-1_PHD.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR PANTHER; PTHR13793:SF79; PROTEIN JADE-1; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 125..175
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 177..291
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT REGION 290..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 512..532
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 573..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 678..750
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..615
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 679..695
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 734..748
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 764 AA; 86405 MW; E2892355250BB889 CRC64;
MSTMCWRIPG DRSGRKGCRC RVVSEEKSLM FIRPKKYIVS SGSEPPELGY VDIRTLADSV
CRYDLNDMDA AWLELTNEEF KEMGMPELDE YTMERVLEEF EQRCYDNMNH AIETEEGLGI
EYDEDVVCDV CQSPDGEDGN EMVFCDKCNI CVHQACYGIL KVPEGSWLCR TCALGVQPKC
LLCPKKGGAM KPTRSGTKWV HVSCALWIPE VSIGSPEKME PITKVSHIPS SRWALVCSLC
NEKFGASIQC SVKNCRTAFH VTCAFDRGLE MKTILAENDE VKFKSYCPKH SSHRKPEESL
GEGAAQESGA PERAPRDPLE PFGSLAQSQE EAHRVSVRKQ KLQQLEDEFY TFVNLLDVAR
ALRLPEEVVD FLYQYWKLKR KVNFNKPLIT PKKDEEDNLA KREQDVLFRR LQLFTHLRQD
LERVRNLTYM VTRREKIKRS VCKVQEQIFN LYTKLLEQER VSGVPSSSCS SSLENMLLFN
SPSVGPDAPK IEDLKWHSAF FRKQMGTSLV HSMKKPHKRD PLQNSAGSEG KTLLKQPDLC
SRREGMVVPE SFLSFEKTFA EARLISAQQK NGVVTPDHGN RRDHRFHCDL GKGDLKDRPF
KQSHKPLRST DVSQRHVDNT RAATSPGVGP SAPGTRREMV PKCNGSLIKV NHNQTAVKVP
TTPGSPVKNW GGFRIPKKGE RQQQGEAHEG ACHPHSDHPY LGLGRVPAKE RAKSKLQSDN
ENDGYVPDVE MSDSESEASE KKCIHAGSTI NRRTDIIRRS ILAS
//
