ID   A0A2Y9FLP3_PHYMC        Unreviewed;       520 AA.
AC   A0A2Y9FLP3;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Cyclic AMP-responsive element-binding protein 3-like protein 1 {ECO:0000313|RefSeq:XP_007125051.1};
GN   Name=CREB3L1 {ECO:0000313|RefSeq:XP_007125051.1};
OS   Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC   Physeteridae; Physeter.
OX   NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007125051.1};
RN   [1] {ECO:0000313|RefSeq:XP_007125051.1}
RP   IDENTIFICATION.
RC   TISSUE=Muscle {ECO:0000313|RefSeq:XP_007125051.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_007125051.1; XM_007124989.4.
DR   AlphaFoldDB; A0A2Y9FLP3; -.
DR   STRING; 9755.ENSPCTP00005028097; -.
DR   Ensembl; ENSPCTT00005030925; ENSPCTP00005028097; ENSPCTG00005020069.
DR   GeneID; 102987194; -.
DR   KEGG; pcad:102987194; -.
DR   CTD; 90993; -.
DR   InParanoid; A0A2Y9FLP3; -.
DR   OrthoDB; 3679507at2759; -.
DR   Proteomes; UP000248484; Unplaced.
DR   GO; GO:0000785; C:chromatin; IEA:Ensembl.
DR   GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005654; C:nucleoplasm; IEA:Ensembl.
DR   GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR   GO; GO:1990837; F:sequence-specific double-stranded DNA binding; IEA:Ensembl.
DR   GO; GO:0046332; F:SMAD binding; IEA:Ensembl.
DR   GO; GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; IEA:Ensembl.
DR   GO; GO:0010629; P:negative regulation of gene expression; IEA:Ensembl.
DR   GO; GO:1903671; P:negative regulation of sprouting angiogenesis; IEA:Ensembl.
DR   GO; GO:0032967; P:positive regulation of collagen biosynthetic process; IEA:Ensembl.
DR   CDD; cd14689; bZIP_CREB3; 1.
DR   Gene3D; 1.20.5.170; -; 1.
DR   InterPro; IPR004827; bZIP.
DR   InterPro; IPR046347; bZIP_sf.
DR   PANTHER; PTHR46004; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A; 1.
DR   PANTHER; PTHR46004:SF1; CYCLIC AMP-RESPONSIVE ELEMENT-BINDING PROTEIN 3-LIKE PROTEIN 1; 1.
DR   Pfam; PF00170; bZIP_1; 1.
DR   PRINTS; PR00041; LEUZIPPRCREB.
DR   SMART; SM00338; BRLZ; 1.
DR   SUPFAM; SSF57959; Leucine zipper domain; 1.
DR   PROSITE; PS50217; BZIP; 1.
DR   PROSITE; PS00036; BZIP_BASIC; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          290..353
FT                   /note="BZIP"
FT                   /evidence="ECO:0000259|PROSITE:PS50217"
FT   REGION          71..97
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          200..259
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          446..520
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        82..96
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        207..251
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        463..478
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   520 AA;  57192 MW;  DFCA4D275D479D3A CRC64;
     MDAVLEPFPA DRLFPGSSFL DLGDLNESDF LNNAHFPEHL DHFAENMEDF SNDLFSSFFD
     DPVLDEKSPL LDMELDSPTP GIQAEHSYSL SGDSAPQSPI VPIKMEDTTQ DVEHGAWVLG
     HKLCSVMVKQ EQSPELPVDP LAASSAMAAA AAMATTPLLG LSPLTRLPVP HQAPGEMTQL
     PVIKAEPQEV NQFLKVTPED LVQMPPTPPS SHGSDSDGSQ SPRSLPPSSP IRPMARSSTA
     ISTSPLLTAP HKLQGTSGPL LLTEEEKRTL IAEGYPIPTK LPLTKAEEKA LKRVRRKIKN
     KISAQESRRK KKEYVECLEK KVETFTSENN ELWKKVETLE NANRTLLQQL QKLQTLVTNK
     ISRPYKMAAT QTGTCLMVAA LCFVLVLGSL VPCLPEFSSG SQTVKEDPMA TDSVYTASQM
     PSRSLLFYDE GPGSWEDGRS ALLPVEPPDG WEIKPGGPAE QRPQDHLQHD HLDSTHETSK
     YLSEAWPKDV GGNSTSPDFS HPKEWFHERD LGPNTTIKLS
//