ID A0A2Y9FSB8_PHYMC Unreviewed; 417 AA.
AC A0A2Y9FSB8;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=RH-like protein {ECO:0000313|RefSeq:XP_007128619.1};
GN Name=LOC102988618 {ECO:0000313|RefSeq:XP_007128619.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007128619.1};
RN [1] {ECO:0000313|RefSeq:XP_007128619.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007128619.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ammonium transporter (TC 2.A.49) family. Rh
CC subfamily. {ECO:0000256|ARBA:ARBA00011036}.
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DR RefSeq; XP_007128619.1; XM_007128557.2.
DR AlphaFoldDB; A0A2Y9FSB8; -.
DR Ensembl; ENSPCTT00005010262; ENSPCTP00005009323; ENSPCTG00005005488.
DR GeneID; 102988618; -.
DR KEGG; pcad:102988618; -.
DR OrthoDB; 5483564at2759; -.
DR Proteomes; UP000248484; Chromosome 3.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR InterPro; IPR029020; Ammonium/urea_transptr.
DR InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR InterPro; IPR002229; RhesusRHD.
DR PANTHER; PTHR11730; AMMONIUM TRANSPORTER; 1.
DR PANTHER; PTHR11730:SF43; BLOOD GROUP RH(CE) POLYPEPTIDE-RELATED; 1.
DR Pfam; PF00909; Ammonium_transp; 1.
DR PRINTS; PR00342; RHESUSRHD.
DR SUPFAM; SSF111352; Ammonium transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 240..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..392
FT /note="Ammonium transporter AmtB-like"
FT /evidence="ECO:0000259|Pfam:PF00909"
SQ SEQUENCE 417 AA; 46142 MW; 920FA2A1135AF339 CRC64;
MGSKYQKSVR APLTLWAFML EVTLILVFFF FTSYETSVKE QKKLMRTYRD FQDVIIMAVL
GLGFLNTSLR RHCWSSVAFN LFMLALGVQL TVLLDGFLNQ LSLRKMVLNL SSIQISTMSA
TSVLISVGVI LGKVNLLQLL LMTLIEVTAF SATRMVGKEV FNMDNHISMM YIHVFAACFG
LTVACCLPKP LPNAAEDKDQ TATSPSLFAM LGTLFLWMFW PSFNSALLDI PDEKKKALFN
TYYALAVSMV TAISVSALAH PQGKINMTHI HNAVLAGGVA VGAPCYLIPS PWLAMVLGLV
AGLISIWGAM YLQVCLQRML DLHDTYGVQY TFGLPGLLGG ITNIVLMALQ VKWTKISMLG
YQILTDSGAF SFTIIMGVGS GLLTGLLLNL KIWKSPHVVN YFNDQTFWKF PRLAVGY
//
