ID A0A2Y9FTS1_PHYMC Unreviewed; 316 AA.
AC A0A2Y9FTS1;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=LOW QUALITY PROTEIN: aquaporin-10 {ECO:0000313|RefSeq:XP_007130387.1};
GN Name=AQP10 {ECO:0000313|RefSeq:XP_007130387.1};
OS Physeter macrocephalus (Sperm whale) (Physeter catodon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti;
OC Physeteridae; Physeter.
OX NCBI_TaxID=9755 {ECO:0000313|Proteomes:UP000248484, ECO:0000313|RefSeq:XP_007130387.1};
RN [1] {ECO:0000313|RefSeq:XP_007130387.1}
RP IDENTIFICATION.
RC TISSUE=Muscle {ECO:0000313|RefSeq:XP_007130387.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.
CC {ECO:0000256|ARBA:ARBA00006175, ECO:0000256|RuleBase:RU000477}.
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DR RefSeq; XP_007130387.1; XM_007130325.1.
DR STRING; 9755.ENSPCTP00005021435; -.
DR GeneID; 102996370; -.
DR KEGG; pcad:102996370; -.
DR CTD; 89872; -.
DR InParanoid; A0A2Y9FTS1; -.
DR OrthoDB; 5490746at2759; -.
DR Proteomes; UP000248484; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015267; F:channel activity; IEA:InterPro.
DR GO; GO:0015791; P:polyol transmembrane transport; IEA:UniProt.
DR GO; GO:0006833; P:water transport; IEA:InterPro.
DR Gene3D; 1.20.1080.10; Glycerol uptake facilitator protein; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR026252; Aquaporin_10.
DR InterPro; IPR000425; MIP.
DR PANTHER; PTHR43829; AQUAPORIN OR AQUAGLYCEROPORIN RELATED; 1.
DR PANTHER; PTHR43829:SF13; AQUAPORIN-10; 1.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR02022; AQUAPORIN10M.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; Aquaporin-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248484};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000477};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000477}.
FT TRANSMEM 20..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 105..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..214
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 270..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 316 AA; 33868 MW; 992C24BD24B1CB97 CRC64;
MAYTQSLAQV KDQLQIHSLL ARQCLAEFLG VFVLTLLIQG TLAQAVTSGG TKGNFFTMFL
ASSLGVRLAS YISGNVSGAH LNPAFSLVMC LLGCLPWAKF PIXALVQLLS AFCASGAXVY
ALYHDALQNY TGGNLTVTGP KETASIFVTY PAPYLSLSNG FLDQVLGTWM LIVGTLAILD
TRNKGAPAGV EPVVVGLLIL AIRLSIGASC GFPINPAWDL DPRLFTYVAA WGPEVFSAGN
GWWXGSLGRA TLSTATHQRL VALHHPEHSE PAQDLECAQP EASDSESPPQ LRCRRRRPPF
RSLGRLAEIQ HPADSN
//
