ID A0A2Y9FVJ8_TRIMA Unreviewed; 250 AA.
AC A0A2Y9FVJ8;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=N-myc proto-oncogene protein isoform X2 {ECO:0000313|RefSeq:XP_012410026.1};
GN Name=LOC101342735 {ECO:0000313|RefSeq:XP_012410026.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_012410026.1};
RN [1] {ECO:0000313|RefSeq:XP_012410026.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012410026.1; XM_012554572.1.
DR AlphaFoldDB; A0A2Y9FVJ8; -.
DR GeneID; 101342735; -.
DR OrthoDB; 3039999at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd11456; bHLHzip_N-Myc_like; 1.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR002418; Tscrpt_reg_Myc.
DR InterPro; IPR012682; Tscrpt_reg_Myc_N.
DR PANTHER; PTHR45851; MYC PROTO-ONCOGENE; 1.
DR PANTHER; PTHR45851:SF2; N-MYC PROTO-ONCOGENE PROTEIN; 1.
DR Pfam; PF00010; HLH; 1.
DR Pfam; PF01056; Myc_N; 1.
DR PRINTS; PR00044; LEUZIPPRMYC.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480}.
FT DOMAIN 167..219
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 1..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 120..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 216..243
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 49..64
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..178
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 250 AA; 28140 MW; C3B58F6B5557B238 CRC64;
MRGAPGNCVG DELTLARRKR AQTATEDTPH SLPGAPRAVS PLDHRQSAGD DEDDEEEDEE
EEIDVVTVEK RRSSSNSKAV TTFTITVRPK NAALGPGRAQ SGELILKRCV PIHQQHNYAA
PSPYVESEDA PPQKKIKNEV SPRPLKSVVP PKAKSLSPRN SDSEDSERRR NHNILERQRR
NDLRSSFLTL RDHVPELVKN EKAAKVVILK KATEYVHSLQ AEEHQLLLEK EKLQARQQQL
LKKIEHARTC
//
