ID A0A2Y9FXT3_TRIMA Unreviewed; 867 AA.
AC A0A2Y9FXT3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Tumor necrosis factor receptor superfamily member 11A {ECO:0000313|RefSeq:XP_012411816.1};
GN Name=LOC101355445 {ECO:0000313|RefSeq:XP_012411816.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_012411816.1};
RN [1] {ECO:0000313|RefSeq:XP_012411816.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012411816.1; XM_012556362.1.
DR AlphaFoldDB; A0A2Y9FXT3; -.
DR STRING; 127582.A0A2Y9FXT3; -.
DR GeneID; 101355445; -.
DR KEGG; tmu:101355445; -.
DR InParanoid; A0A2Y9FXT3; -.
DR OrthoDB; 4574260at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd13411; TNFRSF11A; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR041648; RANK_CRD_2.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR022361; TNFR_11A.
DR InterPro; IPR034040; TNFRSF11A_N.
DR PANTHER; PTHR47134; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11A; 1.
DR PANTHER; PTHR47134:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11A; 1.
DR Pfam; PF18278; RANK_CRD_2; 1.
DR PRINTS; PR01974; TNFACTORR11A.
DR SMART; SM00208; TNFR; 3.
DR SUPFAM; SSF57586; TNF receptor-like; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000313|RefSeq:XP_012411816.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 468..494
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 330..371
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|SMART:SM00208"
FT DOMAIN 373..410
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|SMART:SM00208"
FT DOMAIN 413..453
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|SMART:SM00208"
FT REGION 69..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 679..772
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 800..867
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 867 AA; 92898 MW; 354B40DB44DCA8A0 CRC64;
MESPIKDAIL VYSQWCCITF GRPYLEGLSA RAPGGRQAGA RLPGCLPSPG SGPEGPGCRQ
GLFHEREIRS GRRQTCLKGV PAGGVEREEP RLGSSVPTPA PSAKATWAPQ GGGSDKGGLE
RGERFPTISP PSPPGHQAFR SPESRSRRAA SAPRPRAPLR GRDQRGGRES PPMCMPPGAL
LSRALRGRTG RVGCEKSRGA GPETPGSSAF REARAGDLGG GDGGTWTLQQ AKETDKEHSP
VLGGHRSDMC GQLMTAGSPH YWLRFQIRVS DVLQNRKKSE GSTWMRHGDG QRLPVGRWIP
MKTKRKRPEG RGKYMSSKCT TTSESVCLPC GPDEYLDTWN EEDKCLLHKV CDTGKALVAV
EPGNRTAPRR CACTAGYHWS DDCACCRRNT ECAPGFGAQH PLQLNKDTVC KPCLGGYFSD
AFSSTDKCKP WTNCTVLGKT EKHHGTEKSD VVCSSPLPSR KPPNEPKIYL PSLIILLLFI
SVALVAAVIF GVYYRKKGKT LTANLWHWVN EACSRLSGNK ESSRDGFIST HMATSSQRQV
CEGVLLLTRE KKVFSEDMCY PEAGVCAGEG ATMLSLASEI KGDSFRPMPM EDEYVDRPSQ
TPDCLLVLTQ PGSRSTAPFS GPLEVGENDS LSQCFTGTES MVDSESYNLA KPLCRTDWIP
MSSEKYLQRE VEGGLCPQWA ASSHSADGRT GCRDPPGEDR EPIVGSPKSG PLPQCAYDMG
LPPEDVADKA ERGGQPLDEA DVNPPNPTRG GPGSGSPSCD HPPATGNVTG NSNSTFISSG
QVMNFKGDII VVYVSQTSQE GAAGSGEPAG RPVQEESAGR CDTFAGSGAR LVDKSVDEEA
AQGGPDQTAP PVQEQGLPTP GVPRAWR
//
