ID A0A2Y9FXZ8_TRIMA Unreviewed; 1117 AA.
AC A0A2Y9FXZ8;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=MKL/myocardin-like protein 2 {ECO:0000313|RefSeq:XP_012410105.1};
GN Name=LOC101340697 {ECO:0000313|RefSeq:XP_012410105.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_012410105.1};
RN [1] {ECO:0000313|RefSeq:XP_012410105.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012410105.1; XM_012554651.2.
DR AlphaFoldDB; A0A2Y9FXZ8; -.
DR STRING; 127582.A0A2Y9FXZ8; -.
DR GeneID; 101340697; -.
DR KEGG; tmu:101340697; -.
DR InParanoid; A0A2Y9FXZ8; -.
DR OrthoDB; 2997330at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:UniProt.
DR Gene3D; 6.10.140.2040; -; 1.
DR Gene3D; 6.10.150.10; -; 1.
DR Gene3D; 1.10.720.30; SAP domain; 1.
DR InterPro; IPR043451; Myocardin-like.
DR InterPro; IPR004018; RPEL_repeat.
DR InterPro; IPR003034; SAP_dom.
DR InterPro; IPR036361; SAP_dom_sf.
DR PANTHER; PTHR22793:SF5; MYOCARDIN-RELATED TRANSCRIPTION FACTOR B; 1.
DR PANTHER; PTHR22793; MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED; 1.
DR Pfam; PF02755; RPEL; 2.
DR Pfam; PF02037; SAP; 1.
DR SMART; SM00707; RPEL; 3.
DR SMART; SM00513; SAP; 1.
DR SUPFAM; SSF68906; SAP domain; 1.
DR PROSITE; PS51073; RPEL; 3.
DR PROSITE; PS50800; SAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REPEAT 51..76
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT REPEAT 95..120
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT REPEAT 139..164
FT /note="RPEL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00401"
FT DOMAIN 399..433
FT /note="SAP"
FT /evidence="ECO:0000259|PROSITE:PS50800"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 359..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 489..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 607..687
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 851..924
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..235
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..303
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 304..320
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 361..386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 607..675
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 864..881
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 908..924
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1117 AA; 121633 MW; 5A40BEDBD389A1A2 CRC64;
MDHTGAVDAE DELGPLAHLA PSPQSEAVAH EFQELSLQSS QHLPPLNERK NVLQLRLQQR
RTREQLVDQG IMPPLKSPAA FHEQIKSLER ARTENFLKHK IRSRPDRSEL VRMHILEETF
AEPSLQATQM KLKRARLADD LNEKIAQRPG PMELVEKNIL PVDSSVKEAI IGVGKEDDPQ
TQGDFSFDED SSDALSPDQP ASQESQGSAA SPSEPKVSES PSPVTANTPA QFTSVSPAVP
EFLKTPPADQ PPTRSSAPVL PTNTVSSAKP GPALVKQSHP KNPNDKHRSK KCKDPKPRVK
KLKYHQYIPP DQKGEKNEPQ MDSNYARLLQ QQQLFLQLQI LSQQQQHYNY QTILPAPLKP
LNDKNNNSGN SVLNNSTPST PRQNMSVPVR KPGPLPSSLD DLKVSELKTE LKLRGLPVSG
TKPDLIERLK PYQEMNSSGV AAGSIVAVPT PAIVTSNPEV TMALPVTTLH SSVTSSVSTL
KAELSSTGAS STAHVESVNS PLPISPSPSE QSSLSTDDTN MADTFTEIMT MMSPSQFLCS
SPLRVTNNED SLSPTSSTLS SLELDAAEKD RKLQEKEKQI EELKRKLEQE QKLVEVLKMQ
LEVEKRGQQQ QQQHQQQQQQ HQQQQQQQQR PLDPQPSAPA SSANKLDQKH SSVASTVKDE
ASLSDCSSSR QPIPVASHPG GQPISMGGQT LVAKKAVVIK QEVPVATAEQ QSLVSQFYVS
SQGQPPPAVV AQPQALLTTQ TAQLLLPVSI RGSSVASVQL PVSSLQLQTP PQAGIQPQPQ
IATAAQIPAA ALSSGLTQPV PQKQDTFPRH VLSQPQQVRK VFTNSASPTV LPYQRQPAPA
VQQPFISKTS NSLLQSRNAP LPSVQNGPNP PSKPSSPPPP QQFVVQHSLF GSPVTKTKDP
PRYEEAVRQT RSAQSSLPEV SNAHSQQMDD LFDILIKSGE ISLPIKEEPS PISKMRPVTA
SITTMPVNTV VSRPPPQVQM APPISLEPMS SLSTSLENQL EAFLDGTLPS ANEIPPLQSS
SEDRESFSLI EDLHNELLSH SSMLDHSHSP METSEAQFAA STPCLSLDLS DTNLDNMEWL
DITMPTTSSG LTPLSTTTPS MFSADFLDPQ DLPLPWD
//
