ID A0A2Y9G1L9_TRIMA Unreviewed; 349 AA.
AC A0A2Y9G1L9;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=LOW QUALITY PROTEIN: ral guanine nucleotide dissociation stimulator-like {ECO:0000313|RefSeq:XP_012415065.1};
GN Name=LOC101353366 {ECO:0000313|RefSeq:XP_012415065.1};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_012415065.1};
RN [1] {ECO:0000313|RefSeq:XP_012415065.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012415065.1; XM_012559611.1.
DR STRING; 127582.A0A2Y9G1L9; -.
DR GeneID; 101353366; -.
DR KEGG; tmu:101353366; -.
DR InParanoid; A0A2Y9G1L9; -.
DR OrthoDB; 5362908at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF35; RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR; 1.
DR Pfam; PF00617; RasGEF; 1.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480}.
FT DOMAIN 123..349
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 62..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 72..93
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 349 AA; 39302 MW; A7B8374E8EB5CD2B CRC64;
MRKVFRKYRA ISAILGLWLS QYPEDFYELP DFPCLRLLVD YARLNMPASE LEECAPLLLA
HMEHPESTEA EPEAPEPAPL PAPAVTPELG PVAAPTPEPS WPSLVSTMHR LRQKEKLNIL
SFPPKLVAEQ LTRMHMELFK KVVPYDSLGS IWSQRNKKGK EHLVPTICAT VTQFNSMVYC
VITTCLRNSS MKAXRRATVV ENWIEVTSDC LILRNFSSLH AILCALQSTS ISHFKDTWGE
VSSSVQLGLS LMTRGQEYSP LEGISKFVTL KMNPNRAHKG LQQKEKGVVQ GVILGVYLTD
LVMLDTAFPD FLDEFSVLQE IKLLQYNLSC ELQTQTQLSS NTHLSSKKT
//
