ID A0A2Y9G1N6_TRIMA Unreviewed; 487 AA.
AC A0A2Y9G1N6;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=E3 ubiquitin-protein ligase TRIM58 {ECO:0000313|RefSeq:XP_012415110.2};
GN Name=LOC101347317 {ECO:0000313|RefSeq:XP_012415110.2};
OS Trichechus manatus latirostris (Florida manatee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus.
OX NCBI_TaxID=127582 {ECO:0000313|Proteomes:UP000248480, ECO:0000313|RefSeq:XP_012415110.2};
RN [1] {ECO:0000313|RefSeq:XP_012415110.2}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_012415110.2; XM_012559656.2.
DR AlphaFoldDB; A0A2Y9G1N6; -.
DR STRING; 127582.A0A2Y9G1N6; -.
DR KEGG; tmu:101347317; -.
DR InParanoid; A0A2Y9G1N6; -.
DR OrthoDB; 3453019at2759; -.
DR Proteomes; UP000248480; Unplaced.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19780; Bbox2_TRIM39-like; 1.
DR CDD; cd16606; RING-HC_TRIM58_C-IV; 1.
DR CDD; cd15816; SPRY_PRY_TRIM58; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR035787; SPRY/PRY_TRIM58.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR042699; TRIM58_RING-HC.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF393; E3 UBIQUITIN-PROTEIN LIGASE TRIM58; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000248480};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 16..61
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 92..133
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 274..469
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT COILED 195..243
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 487 AA; 55729 MW; 906633495912F64C CRC64;
MASGPPGERL REEARCPVCL DFLQEPVSVN CGHSFCFRCI SEFCQKSDSA QGGVYACPQC
RGPFSPESFR PNRQLASLVE SVRQLGLGTG PTGVRLCLRH GEELSRFCEE DQAALCWICD
TTPEHRSHLT MPLQEAARCY QVKLQTALGL VRKEMEEALT QEANVVKKTV IWKEKVEVRR
QRFRLEFEKH RGFLAQEEQL QLRRLEEEER ATIQRLRESK NRLAQHSKAL KELAKELEER
CQRPAVGLLE DVREALSRSK AVTQLEPETI PMELRTMCHI PGMREMLRKF QVDVKLDPAT
AHPSLLLTAD LRSVQDGELW RDVPNNPERF DTWPCILGLQ NFSSGRHYWE VMVGERAEWG
LGVCQDTVSR KGETTPSPEN GIWAMWLLKG NEYMVLASPS VPVLQMERPH CIGIFLDYEA
GEISFYNVTN WSHIYTFNRL FSGVLRPYFF ICDMNPLILP PITVVESENW ASSGLLDSAS
NFREDHS
//
