ID A0A2Y9IFE8_ENHLU Unreviewed; 487 AA.
AC A0A2Y9IFE8;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=E3 ubiquitin-protein ligase TRIM58 {ECO:0000313|RefSeq:XP_022347392.1};
GN Name=LOC111139434 {ECO:0000313|RefSeq:XP_022347392.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022347392.1};
RN [1] {ECO:0000313|RefSeq:XP_022347392.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022347392.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR RefSeq; XP_022347392.1; XM_022491684.1.
DR AlphaFoldDB; A0A2Y9IFE8; -.
DR STRING; 391180.A0A2Y9IFE8; -.
DR KEGG; elk:111139434; -.
DR OrthoDB; 3453019at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19780; Bbox2_TRIM39-like; 1.
DR CDD; cd16606; RING-HC_TRIM58_C-IV; 1.
DR CDD; cd15816; SPRY_PRY_TRIM58; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR035787; SPRY/PRY_TRIM58.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR042699; TRIM58_RING-HC.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR24103; E3 UBIQUITIN-PROTEIN LIGASE TRIM; 1.
DR PANTHER; PTHR24103:SF393; E3 UBIQUITIN-PROTEIN LIGASE TRIM58; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR Pfam; PF15227; zf-C3HC4_4; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 16..61
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 97..133
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 273..464
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT COILED 196..243
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 487 AA; 55512 MW; CE182AF04CC0FA06 CRC64;
MASGAPGERL RDEARCPVCL DFLQDPVSVA CGHSFCRRCI SEFCEKSTST QGGQYTCPQC
RGPFGLDSLR PNRQLASLVD GVRQLGLGVG PGGVHQCARH GEDLTLFCED DQEALCWVCD
TTLEHRDHGT VPLQEATRGY QAKLQMALEL VRKEMEETFT QEANLGKKTV IWKEKVEMQR
QRFRLEFEKY RGFLALEEQL QLRRLEEEER ATLQRLRENK NRLGQQSRAL RELAQELEEK
SQRPALELLE GVRGVLSRSK DVTQPELEPV PMELRTTCRI PGMREMLRKF QVDVKLDPST
AHPSLLLTAN LRSVQDGELW RELPNNPERF DTWPCILGLQ TFSSGRHYWE VVVGDRAEWG
LGVCQETMPR KGETTPSPEN GVWAMWLLKG NEYMVLASPS VPLLHLDRPR CIGIFLDYEA
GEISFYNVTN GSYIYTFNQL FSGILRPYFF ICDTIPLTLP SMTDMESGDW ACRDHLDSAS
SVRHDCS
//
