ID A0A2Y9IJ40_ENHLU Unreviewed; 1734 AA.
AC A0A2Y9IJ40;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Ankyrin repeat domain-containing protein 26 {ECO:0000313|RefSeq:XP_022347259.1};
GN Name=LOC111139305 {ECO:0000313|RefSeq:XP_022347259.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022347259.1};
RN [1] {ECO:0000313|RefSeq:XP_022347259.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022347259.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_022347259.1; XM_022491551.1.
DR STRING; 391180.A0A2Y9IJ40; -.
DR KEGG; elk:111139305; -.
DR OrthoDB; 2385613at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 4.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR039497; CC144C-like_CC_dom.
DR InterPro; IPR021885; DUF3496.
DR PANTHER; PTHR24147; ANKYRIN REPEAT DOMAIN 36-RELATED; 1.
DR PANTHER; PTHR24147:SF60; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 26-RELATED; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF14915; CCDC144C; 1.
DR Pfam; PF12001; DUF3496; 1.
DR SMART; SM00248; ANK; 8.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 7.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482}.
FT REPEAT 81..113
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 114..146
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 147..179
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 180..212
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 230..262
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 303..335
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 336..368
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 1034..1336
FT /note="CCDC144C-like coiled-coil"
FT /evidence="ECO:0000259|Pfam:PF14915"
FT DOMAIN 1545..1653
FT /note="DUF3496"
FT /evidence="ECO:0000259|Pfam:PF12001"
FT REGION 397..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 457..476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 547..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 724..827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 887..928
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1040..1138
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1171..1332
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1361..1492
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 424..439
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..567
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..671
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..706
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 747..770
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 794..823
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1734 AA; 198448 MW; 30B642DB07D23566 CRC64;
MKKFFGFGTG KGRSSPVFRM ELMNGLGAPV DKKEEVNESP RRYNIHVKDF KEIHRAAVMG
NILKMQRLLL LGKDVNKRDK KKRTPLHLAC TIGHADMVDF LVERKCELDL YDQDCRTPLM
KAVQYQEEAC VTILLEHGAN PRLTDNFGNT ALHYAVAGEN TSIAEKLILY HANIEARNKF
ELTPFLLAIT ENKYQMVELL IGKKADVHVV DKSKRYNNSE FLRVKLCLCY FRTALMLAAI
SKSPDVVRLL LQQGVNTSSR DECGWTAGHY AVFGGFDVYV LEFGDREIKN SPFPQEALGF
DGFELTPFLL AVNENKHQMV ELLIGKKADV HVVDKSKRTA LMLAATSKSP DVVRLLLQQG
INPSSRDECG WTAEDYAAFS GFDVNRQIIA QHTEERLKNF SQNNNPAGEG EERPAIGTKD
DGITESVPQE QTVNDCLTSA DRADKNDRHV MLSALGFAEQ NEESPWDSES NSESLPETYI
DHLSGNADQK GTSPLNEQVG DVFYIPSCMS GSRNFKMAKL EDTRNVGIPV AHMDSLEKYS
FLKPTVEEKD SVPKKGGQME EKQTSKSDSP GKCSYLKPAV EGKGFVPNEP REMEDIQASQ
SDSPGKYSYL KPAVEGKEFI PNQPREVEEI QASQSDSPGK YSYLKPGVEV NHSLPNKPGE
MEEKETSESD FSAELDLEMT TEEEEESLSE SENKHLQIEE TEKHQNDEMA VLESIYASAA
AGLMHPIGSG KTDNNPCPIT ENEESDGDPA LDTKELRKGE KEKQTSKESV ITPRFEKAPS
LTSRPLRMND DSTSSGMDQD EGRPAKKTSS EEEEVKKQIP CMDDLDDLTP SSETISEGFH
MPCSNYMTCM SLIEQHGMDC KDSVSLLKIQ NAVLSYRRLI ELKKYHCGQL KRKNKKMENK
AKGLQKELSE KKEMISKLEL QKVEWEQELC SLRRLFPSTS PNPYRLPWCE ARATGCARRS
HLDSQLQSLT GPEVVEEWND TKKQLCREQD ARILQDGILN NHLCKQKEIE MDNKRSSGIS
NSCEKEKYLL HNKYMLEDQI AMLRLEIDTI NNQNQEKERK YCEDIEILKE KHVSLQKTIK
LTEERLTNTE LQHSGEINAL TIENTMLKSK LENEKQNKER LDEKVESYRA RLATAIQDYD
QSQTSKRDLE LAFQRAKGEW FRVQDKLNFD VSKLKEDNEL LSQNLSEAES KFNTLETELH
STRDALREKT LVLERVQRDL SQTQCQKKEI EHAYQSAQDK VSKYIGKQES LKERLSQLQS
ENMLLQQQLD DAYNKASSKE KVVINIQDQF QDIIKKLQAE SQKQALVIEA SKQELINERN
LLREKMYVYE KEKVEREVAV RQLQEELADT LKKQSMSEAS LEVTSRCRMN LEDEVKDLKE
KLAQIRNQLQ DAQERHAEAV MRIETLKDHV QKLEVENAEL KDTIKKQVGK IEQLQENTLS
TCSSDDEKEQ IKKFIELKQS LECSLNQEMK KNGELEKEIT RFKKLLKATR KKLSEYGNED
LSFHGDLRTS HTETDIQINM LKHKTQVASQ ESLAQLRENN NASVRSQMEL RIKELEFELF
KMKSSQEDLT KTELDRYKHL YLEEVMHRTS LTNELNKTSE RLAETSTRLL MEKQQKQTLL
DTINMRPALD LPYGRKVNNS SLFNRNVALR ENMMIPTSNS WHSSNDIGTF LTKMQQELEK
NITRELEEVA AEFESGSSGG ATSLESTFER HINCDDVQKA YREYSEFLKK KYSI
//
