ID A0A2Y9IQJ2_ENHLU Unreviewed; 512 AA.
AC A0A2Y9IQJ2;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Zinc finger CCCH-type with G patch domain-containing protein {ECO:0000256|ARBA:ARBA00022414};
GN Name=LOC111141941 {ECO:0000313|RefSeq:XP_022350526.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022350526.1};
RN [1] {ECO:0000313|RefSeq:XP_022350526.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022350526.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBUNIT: Interacts with CHD4/Mi-2; the interaction is direct.
CC {ECO:0000256|ARBA:ARBA00011506}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_022350526.1; XM_022494818.1.
DR AlphaFoldDB; A0A2Y9IQJ2; -.
DR STRING; 391180.A0A2Y9IQJ2; -.
DR KEGG; elk:111141941; -.
DR OrthoDB; 3060898at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd20384; Tudor_ZGPAT; 1.
DR Gene3D; 2.30.30.1190; -; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR041367; Znf-CCCH_4.
DR InterPro; IPR000571; Znf_CCCH.
DR PANTHER; PTHR46297; ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46297:SF1; ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF18044; zf-CCCH_4; 1.
DR SMART; SM00443; G_patch; 1.
DR SMART; SM00356; ZnF_C3H1; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS50103; ZF_C3H1; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00723}.
FT DOMAIN 177..203
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 316..362
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT ZN_FING 177..203
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 90..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 268..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 365..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 491..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..118
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..512
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 512 AA; 55996 MW; 7016B6816A25F981 CRC64;
MDEESLQSAL RTYDGQLRQV ELALGAGLDA AELADLRRLQ GDLKELIELT EASLVSVRKS
KLLAALDGPR AAPDDAEYLA FQKAVAEGVE GPAAPGAEPE TGPEREAQPE ARGCGQEQEQ
DEGEDDDEGE WSGRKVNAPF YSPWGTLEYH NAMIVGAEAA GDGPAAVRVL YLYPTHKSLK
PCPFFLEGKC RFQEHCRFSH GQVVSVDELR PFQDPDLSSL QAGSACLAKQ QDGLWYPARI
TDVDNGYYTV KFDSLLLKEA VVEGDSILPP LRTDPTGSSD SDSGDADDSS YARVVEPGTA
DHGTCSSAFG GWEVHTRGIG SRLLAKMGYE FGKGLGRHAE GRVEPIHAVV LPRGKSLDQC
IETLQKRTRS SRAGTPRLPK CQERGHTRPP PRSVFDFLNE TLQCRAPGAL EAGAAPPGRR
SSKEMYHAGK SAKRALSLRL FQTEKKIEQT QQDIRGIQKA LARNTGRHSV TAAQLQERLA
RAQRELGQLR AQEAGLQREQ RKADTHKKMT EF
//
