ID A0A2Y9ITD5_ENHLU Unreviewed; 510 AA.
AC A0A2Y9ITD5;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform X7 {ECO:0000313|RefSeq:XP_022350604.1};
GN Name=LOC111141988 {ECO:0000313|RefSeq:XP_022350604.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022350604.1};
RN [1] {ECO:0000313|RefSeq:XP_022350604.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022350604.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_022350604.1; XM_022494896.1.
DR AlphaFoldDB; A0A2Y9ITD5; -.
DR OrthoDB; 25046at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR CDD; cd01274; PTB_Anks; 1.
DR CDD; cd09499; SAM_AIDA1AB-like_repeat1; 1.
DR CDD; cd09500; SAM_AIDA1AB-like_repeat2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 2.
DR InterPro; IPR033635; ANKS1/Caskin.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR006020; PTB/PI_dom.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR041880; SAM_ANKS1_repeat1.
DR InterPro; IPR041882; SAM_ANKS1_repeat2.
DR PANTHER; PTHR24174; ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR24174:SF3; ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1B; 1.
DR Pfam; PF00640; PID; 1.
DR Pfam; PF00536; SAM_1; 2.
DR SMART; SM00462; PTB; 1.
DR SMART; SM00454; SAM; 2.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 2.
DR PROSITE; PS01179; PID; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 2.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482}.
FT DOMAIN 39..102
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 110..169
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 310..443
FT /note="PID"
FT /evidence="ECO:0000259|PROSITE:PS01179"
FT REGION 170..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 448..467
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..213
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 510 AA; 57851 MW; DA6C52C23F37696A CRC64;
MMWQCHLSAQ DYRYYPVDGY SLLKRFPLHP LTGPRCPVQT VGQWLESIGL PQYENHLMAN
GFDNVQFMGS NVMEDQDLLE IGILNSGHRQ RILQAIQLLP KMRPIGHDGY HPTSVAEWLD
SIELGDYTKA FLINGYTSMD LLKKIWEVEL INVLKINLIG HRKRILASLG DRLHDDPPQK
PPRSITLRDP SGNHTPPQLS PSLSQSTYTT GGSLDVPHII MQGDARRRRN ENYFDDIPRS
KLERQMAQQS SVCEIWTNQN AGFPFSAIHQ VHNTGDWGEP SITLRPPNEA TASTPVQYWQ
HHPEKLIFQS CDYKAFYLGS MLIKELRGTE STQDACAKMR ANCQKSTEQM KKVPTIILSV
SYKGVKFIDA TNKNIIAEHE IRNISCAAQD PEDLSTFAYI TKDLKSNHHY CHVFTAFDVN
LAYEIILTLG QAFEVAYQLA LQARKGGHSS TLPESFENKP SKPIPKPRVS IRKSVIDPSE
QKTLANLPWI VEPGQEAKRG INTKYETTIF
//
