ID   A0A2Y9IVL2_ENHLU        Unreviewed;       236 AA.
AC   A0A2Y9IVL2;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Haloacid dehalogenase-like hydrolase domain-containing protein 2 {ECO:0000256|ARBA:ARBA00039666};
GN   Name=LOC111142481 {ECO:0000313|RefSeq:XP_022351389.1};
OS   Enhydra lutris kenyoni (northern sea otter).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Lutrinae; Enhydra.
OX   NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022351389.1};
RN   [1] {ECO:0000313|RefSeq:XP_022351389.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022351389.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily.
CC       {ECO:0000256|ARBA:ARBA00007958}.
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DR   RefSeq; XP_022351389.1; XM_022495681.1.
DR   AlphaFoldDB; A0A2Y9IVL2; -.
DR   Proteomes; UP000248482; Unplaced.
DR   GO; GO:0016791; F:phosphatase activity; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   CDD; cd07509; HAD_PPase; 1.
DR   Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 2.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR006357; HAD-SF_hydro_IIA.
DR   InterPro; IPR023214; HAD_sf.
DR   InterPro; IPR006355; LHPP/HDHD2.
DR   NCBIfam; TIGR01460; HAD-SF-IIA; 1.
DR   NCBIfam; TIGR01458; HAD-SF-IIA-hyp3; 1.
DR   PANTHER; PTHR19288; 4-NITROPHENYLPHOSPHATASE-RELATED; 1.
DR   PANTHER; PTHR19288:SF46; HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2; 1.
DR   Pfam; PF13344; Hydrolase_6; 1.
DR   Pfam; PF13242; Hydrolase_like; 1.
DR   SFLD; SFLDG01139; C2.A:_Pyridoxal_Phosphate_Phos; 1.
DR   SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR   SUPFAM; SSF56784; HAD-like; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|RefSeq:XP_022351389.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248482}.
SQ   SEQUENCE   236 AA;  25787 MW;  4A40B8883C06B1B0 CRC64;
     MAARRALKAV LVDLNGTLHV EDAAVPGAQE ALKRLRGASV MVRFVTNTTK ESKQDLLDRL
     KKLEFDISED EIFTSLTAAR NLVEQKQVRP MLLVDDRALP DFKGIQTSDP NAVVIGLAPE
     HFHYQILNQA FRLLLDGAPL IAIHKARYYK RKDGLALGPG PFVTALEYAT DTKATVVGKP
     EKTFFLEALR GTGCEPEEAV MIGDDCRDDV GGAQNVGMLG ILVKTAASCE HDCPLM
//