ID A0A2Y9IW10_ENHLU Unreviewed; 417 AA.
AC A0A2Y9IW10;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=ADP-ribosylation factor GTPase-activating protein 1 isoform X1 {ECO:0000313|RefSeq:XP_022350135.1, ECO:0000313|RefSeq:XP_022350136.1};
GN Name=LOC111141680 {ECO:0000313|RefSeq:XP_022350135.1,
GN ECO:0000313|RefSeq:XP_022350136.1, ECO:0000313|RefSeq:XP_022350140.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022350140.1};
RN [1] {ECO:0000313|RefSeq:XP_022350135.1, ECO:0000313|RefSeq:XP_022350136.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022350135.1,
RC ECO:0000313|RefSeq:XP_022350136.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; XP_022350135.1; XM_022494427.1.
DR RefSeq; XP_022350136.1; XM_022494428.1.
DR RefSeq; XP_022350140.1; XM_022494432.1.
DR KEGG; elk:111141680; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR CDD; cd08830; ArfGap_ArfGap1; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR46395; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1; 1.
DR PANTHER; PTHR46395:SF1; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 7..124
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 126..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 296..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 335..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..140
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 306..320
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..381
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 417 AA; 45471 MW; 82C13FB8815C447A CRC64;
MASPRTRKVL KEVRAQDANS VCFECGAFNP QWVSVTYGIW ICLECSGKHR GLGVHLSFVR
SVTMDKWKDV ELEKTKAGGN AKFREFLESQ EDYDPCWSLQ DKYNSRAAAL FRDKVATLAE
GKEWSLESSP AQNWTPPQPK MLPSTAHRAP GHPQNSTSSS DKAFEDWLND DLGSYQGAQE
NRYVGFGNTV PPPKREEDFL SSAVSSLCSG WSSFTTGASK FASAAKEGAT KFGSQASQKA
SELGQSLNEN VLKPAQEKVK EGRLFDDVSS GVSQLASKVQ GVGSRGWRDV TAFFSGRAED
PSDRPLEGQS YQNSGGDHAL NRTVDQSFWE TFGNAESTKG HRSPSSDSWT CADASAEKRS
SDSWDVWGSG SASTNKNSDH SDLGEAWGGS GEGRAKTAKK ATPPVMPVDE GWDNQDW
//
