ID   A0A2Y9J934_ENHLU        Unreviewed;        69 AA.
AC   A0A2Y9J934;
DT   12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT   12-SEP-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Beta-defensin 1 {ECO:0000256|ARBA:ARBA00040807};
DE   AltName: Full=Defensin, beta 1 {ECO:0000256|ARBA:ARBA00041630};
GN   Name=LOC111144381 {ECO:0000313|RefSeq:XP_022354365.1};
OS   Enhydra lutris kenyoni (northern sea otter).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC   Lutrinae; Enhydra.
OX   NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022354365.1};
RN   [1] {ECO:0000313|RefSeq:XP_022354365.1}
RP   IDENTIFICATION.
RC   TISSUE=Blood {ECO:0000313|RefSeq:XP_022354365.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC       Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR   RefSeq; XP_022354365.1; XM_022498657.1.
DR   AlphaFoldDB; A0A2Y9J934; -.
DR   STRING; 391180.A0A2Y9J934; -.
DR   KEGG; elk:111144381; -.
DR   OrthoDB; 4335232at2759; -.
DR   Proteomes; UP000248482; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   InterPro; IPR001855; Defensin_beta-typ.
DR   PANTHER; PTHR21388:SF9; BETA-DEFENSIN 1; 1.
DR   PANTHER; PTHR21388; BETA-DEFENSIN-RELATED; 1.
DR   Pfam; PF00711; Defensin_beta; 1.
DR   SUPFAM; SSF57392; Defensin-like; 1.
PE   4: Predicted;
KW   Antibiotic {ECO:0000256|ARBA:ARBA00023022};
KW   Antimicrobial {ECO:0000256|ARBA:ARBA00022529};
KW   Defensin {ECO:0000256|ARBA:ARBA00022940};
KW   Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..69
FT                   /note="Beta-defensin 1"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5016105484"
SQ   SEQUENCE   69 AA;  7420 MW;  AF909DEE5CD8923F CRC64;
     MRALSFLLLI LCLVSSHLAP GAGFLSGLGQ RSDHYMCVRK GGTCNFSPCP LFTRSEGTCY
     GGKAKCCMR
//