ID A0A2Y9JA68_ENHLU Unreviewed; 437 AA.
AC A0A2Y9JA68;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=LOW QUALITY PROTEIN: bile acid-CoA:amino acid N-acyltransferase-like {ECO:0000313|RefSeq:XP_022356589.1};
GN Name=LOC111145724 {ECO:0000313|RefSeq:XP_022356589.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022356589.1};
RN [1] {ECO:0000313|RefSeq:XP_022356589.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022356589.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC {ECO:0000256|ARBA:ARBA00006538}.
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DR RefSeq; XP_022356589.1; XM_022500881.1.
DR STRING; 391180.A0A2Y9JA68; -.
DR KEGG; elk:111145724; -.
DR OrthoDB; 5356064at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR GO; GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
DR Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR InterPro; IPR014940; BAAT_C.
DR InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR PANTHER; PTHR10824:SF18; BILE ACID-COA:AMINO ACID N-ACYLTRANSFERASE; 1.
DR Pfam; PF08840; BAAT_C; 1.
DR Pfam; PF04775; Bile_Hydr_Trans; 1.
DR PIRSF; PIRSF016521; Acyl-CoA_hydro; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 402..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..144
FT /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT acid N-acetyltransferase"
FT /evidence="ECO:0000259|Pfam:PF04775"
FT DOMAIN 207..384
FT /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF08840"
FT ACT_SITE 235
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT ACT_SITE 329
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT ACT_SITE 363
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
SQ SEQUENCE 437 AA; 48513 MW; 926DC8A1CF694E60 CRC64;
MIQLTATPAN ALVDEPVHIR ATGLSPFQVV ILQASLADEK GNLFHSQAYC KANEAGXVDL
QQAPLLGGDY IGVHPMGLFW SLKPEKFLMK LVKRDVMNSP FLVQIKLYDS NLELTDIATT
APKVSLTLER WYVAPGVKRI QVREGHLRGA LFLPPRKGCF PGIIDLFGGI GGLIEYRASL
LASRGFASLA LAYFNYEDLP AQPEKTELDY FEEAVNFLLR HPKVLGPGIG IVSISKGAEI
GLSMAIHLKQ VTATVLINGP NFILRIPQVY RGQISKPLAF SPQSLSINAL GLVEFQHGFE
EARCEASETS LLPIEKAQGH FLFIVGEDDK NLNSKVYAEQ ATQQLSRYRK NNWTLLSYPG
AGHLLEPPYS PLSLLLSSAI QTQKQHSLAI MNVHGCVPFK LYLWKLTFAF HIIFTCNRIV
IFFFFFFLSI GQCKSHA
//
