ID A0A2Y9JFX3_ENHLU Unreviewed; 434 AA.
AC A0A2Y9JFX3;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Serpin E3 isoform X1 {ECO:0000313|RefSeq:XP_022358564.1};
GN Name=LOC111147013 {ECO:0000313|RefSeq:XP_022358564.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022358564.1};
RN [1] {ECO:0000313|RefSeq:XP_022358564.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022358564.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the serpin family.
CC {ECO:0000256|RuleBase:RU000411}.
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DR RefSeq; XP_022358564.1; XM_022502856.1.
DR AlphaFoldDB; A0A2Y9JFX3; -.
DR STRING; 391180.A0A2Y9JFX3; -.
DR KEGG; elk:111147013; -.
DR OrthoDB; 3218836at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR PANTHER; PTHR11461:SF129; SERPIN A13-RELATED; 1.
DR Pfam; PF00079; Serpin; 1.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..434
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015868319"
FT DOMAIN 35..395
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 434 AA; 47972 MW; 0221D211080ED7B2 CRC64;
MGPALVTLLL LHSCLHGGQG DLREDLTLLK TELAIRLYQD AAAPRNGTNV VISPAGVSLP
LEILQFGAQG NTGRQLAQVL GYTVHDRRVK EVLRTAYTTL LNSGQGTRME LACTLFVQAG
TPLSPCFVEQ ISRWANSSVE PAHLSEPSGT SMQAKGWASR KIAGGPTGEH GGGAGLAQLA
LVSTMSFQST WRQRFSSRDT QLLPFTGAQG LVLQVPMMYQ MAEVNYGQFQ DPAGHQVRVL
ELPYLGSTVS LLLVLPRDKD TPLSLIEPHL TASILHVWTS SLRRARMDVF LPRFRIQNHF
NLKSILNSWG VTNLFDPLKA NLKGISGQDD FYVSEAIHKA KIEVSEEGTE ASTAAALLLL
KRSRIPFFKA DRPFFFFLRE PNTGRTVFFD RIQINIYHHL SSNKRPFVRC GLEQAFLLAS
FYGFTIFPVS CRVS
//
