ID A0A2Y9JIN0_ENHLU Unreviewed; 1011 AA.
AC A0A2Y9JIN0;
DT 12-SEP-2018, integrated into UniProtKB/TrEMBL.
DT 12-SEP-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Polyhomeotic-like protein 3 isoform X1 {ECO:0000313|RefSeq:XP_022360903.1};
GN Name=LOC111148550 {ECO:0000313|RefSeq:XP_022360903.1};
OS Enhydra lutris kenyoni (northern sea otter).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae;
OC Lutrinae; Enhydra.
OX NCBI_TaxID=391180 {ECO:0000313|Proteomes:UP000248482, ECO:0000313|RefSeq:XP_022360903.1};
RN [1] {ECO:0000313|RefSeq:XP_022360903.1}
RP IDENTIFICATION.
RC TISSUE=Blood {ECO:0000313|RefSeq:XP_022360903.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_022360903.1; XM_022505195.1.
DR AlphaFoldDB; A0A2Y9JIN0; -.
DR STRING; 391180.A0A2Y9JIN0; -.
DR KEGG; elk:111148550; -.
DR OrthoDB; 5399754at2759; -.
DR Proteomes; UP000248482; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd09577; SAM_Ph1_2_3; 1.
DR Gene3D; 3.30.60.160; -; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR012313; Znf_FCS.
DR InterPro; IPR038603; Znf_FCS_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF88; POLYHOMEOTIC-LIKE PROTEIN 3; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF21319; zf-FCS_1; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS51024; ZF_FCS; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000248482};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00367}.
FT DOMAIN 804..838
FT /note="FCS-type"
FT /evidence="ECO:0000259|PROSITE:PS51024"
FT DOMAIN 947..1011
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 115..161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 237..296
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 321..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 490..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 628..648
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 855..875
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 893..917
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 237..273
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..296
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..352
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..410
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1011 AA; 109413 MW; 6E324335458664DB CRC64;
MAEAEFKDHS TAMDSEPNPG TSSVSTTTSS TTTTTITTSS SRMQQPQISV YSGSDRHAVQ
VIQQALHRPP SSAAQYLQQM YAAQQQHLML HTAALQQQHL SSSQLQSLAA VQASLSSGRP
STSPTGSVTQ QSSMSQTSIN LSTSPTPAQL ISRSQASSST SGSITQQTML LGSTSPTLTA
SQAQMYLRAQ MLIFTPATTV AAVQSDIPVV SSSSSSSCQS AATQVQNLTL RSQKLGVLSS
SQNGPPKSTS QTQSLTICHN KTTVTSSKIS QRDPSPESNK KGESPSLESR STAVTRTSSI
HQLIAPASYP PIQPHPLIKH QQIPLHSPPP KVSHHQLILQ QQQQQIQPIT LQNPTQDPPP
SQHCMPLQNH GLPPAPSNAQ SQHCSPIQSH PPPLTMSPSQ SQSAQQSVVV SPPPPHSPSQ
SPTIIIHPQA LIQPHSLVSS ALQPGPNLQQ STANQVQPTA QLNLPSHLPL PASPVVHIGP
VQQSALVSPG QQIVSPTSHQ QYSTLQSSPI PIATPPQMSA SPPAQIPPLP LQSMQSLQVQ
PEILSQGQVL VQNALVSEEE LPAAEALVQL PFQTLPPPQT VAVNLQVQPP APVDPPVGMH
LNQCHLHKVF SLKVYQVEDV CEEEMPEESD ECVRMDRTPP PPTLSPAAIT VGREDLTSEH
PLLEQVELPA VASVSASVIK SPSDPSHVSV PPPPLLLPAA TTRSNSTSVP SSIPSIENKP
PQAIVKPQIL THVIEGFVIQ EGLEPFPVSR SSLLIEQPVK KRPLLDNQVI NSVCVQPELQ
NNTKHADNSS DTEMEDMIAE ETLEEMDSEL LKCEFCGKMG YANEFLRSKR FCTMSCAKRY
NVSCSKKFAL SRWNRKPDNQ SLGHRGRRPS GPDGAAREHI LRQLPITYPS AEEDLASHEE
SVPSAMTTRL RRQSERERER ELRDVRIRKM PENSDLLPVA QTEPSIWTVD DVWAFIHSLP
GCQDIADEFR AQEIDGQALL LLKEDHLMSA MNIKLGPALK ICARINSLKE S
//
